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020 _a9783030113926
024 7 _a10.1007/978-3-030-11392-6
_2doi
040 _bspa
_cES-MaUEC
_dES-MaUEC
050 4 _aRC643
_b2019 EB
245 0 0 _aChronic Lymphocytic Leukemia
_cedited by Michael Hallek, Barbara Eichhorst, Daniel Catovsky
264 1 _aCham
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (VI, 179 páginas)
_b23 ilustraciones, 19 ilustraciones a color
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aHematologic Malignancies
_x2197-9766
490 0 _aMedicine (Springer-11650)
505 0 _aPathophysiolgoy -- Diagnostics -- Clinical Presentation -- Prognostic Markers -- Treatment -- Follow-up and Complications -- Related Entities.
520 3 _aThis book summarizes current knowledge on chronic lymphocytic leukemia (CLL), taking into account the most recent research. All aspects are considered, including pathophysiology, clinical presentation, diagnosis, prognosis, treatment, follow-up, and complications and their management. Readers will find important information on the various prognostic markers as well as practical guidance on the use of different diagnostic procedures. A key focus of the book is the changing treatment paradigm in CLL as progress in understanding of pathogenesis and pathophysiology leads to the identification of new potential therapeutic targets. General treatment concepts are clearly described, and it is explained how choice of treatment for CLL depends on stage, age, and performance status as well as specific genetic aberrations. In addition, frontline therapeutic strategies for disease relapse, including allogeneic stem cell transplantation, are reported. Looking beyond CLL, the diagnosis and therapy of T-cell prolymphocytic leukemia and T-cell large granular lymphocyte leukemia, two rare CLL-related entities, are addressed. .
988 _aSpringer_Medicine_2019
650 7 _aLeucemia linfática crónica
_2embne
_9667051
700 1 _aHallek, Michael.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aEichhorst, Barbara.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aCatovsky, Daniel.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_9106996
776 0 8 _iPrinted edition:
_z9783030113919
776 0 8 _iPrinted edition:
_z9783030113933
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-11392-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _dz
_b02/2023
_eb
_zSI