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020			_a9783319543680
024	7		_a10.1007/978-3-319-54368-0 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRB45 _b2019 EB
245	0	0	_aCell and Gene Therapies _cedited by Miguel-Angel Perales, Syed A. Abutalib, Catherine Bollard
264		1	_aCham _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VI, 288 páginas) _b12 ilustraciones, 11 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances and Controversies in Hematopoietic Transplantation and Cell Therapy _x2569-1376
490	0		_aMedicine (Springer-11650)
505	0		_aHistorical perspective and current focus -- Part I: Genetically modified T cells (Chimeric antigen receptors and T cell receptors): Chimeric antigen receptor-T cells: Antigen selection, CAR development and future prospects -- Chimeric antigen receptor-T cells for leukemias in children: Methods, data and challenges -- Chimeric antigen receptor-T cells for leukemias in adults- Methods, data and challenges -- Chimeric antigen receptor-T cells for lymphomas: Methods, data and challenges -- T-cell receptors-gene modified T-cells for cancer -- Methods, data and challenges. -- Part II: Beyond chimeric antigen receptor and T-cell receptors - Data, Consensus & Challenges: Cytotoxic T cells for infections: From donor-specific to "off the shelf" -- Donor lymphocyte infusion in different transplant settings: When and how?- T-regulatory cells: Broadening applicability -- Tumor infiltrating lymphocytes: Current concepts and practices -- Part III: Beyond T-cells: Natural killer cells: What have we learned?- Dendritic cells in hematopoietic cell transplantation -- Mesenchymal stem cells: From bench to bedside and back -- Cell Therapies: Regulatory concerns and data collection -- Part IV: Gene Therapy: Gene therapy for hematologic malignancies and in transplant setting -- Gene therapy for nonmalignant disorders -- Future prospects of cell and gene therapies.
520	3		_aIn this book, experts in the field express their well-reasoned opinions on a range of complex, clinically relevant issues across the full spectrum of cell and gene therapies with the aim of providing trainee and practicing hematologists, including hematopoietic transplant physicians, with information that is relevant to clinical practice and ongoing research. Each chapter focuses on a particular topic, and the concise text is supported by numerous working tables, algorithms, and figures. Whenever appropriate, guidance is provided regarding the availability of potentially high-impact clinical trials. The rapid evolution of cell and gene therapies is giving rise to numerous controversies that need to be carefully addressed. In meeting this challenge, this book will appeal to all residents, fellows, and faculty members responsible for the care of hematopoietic cell transplant patients. It will also offer a robust, engaging tool to aid vital activities in the daily work of every hematology and oncology trainee.
988			_aSpringer_Medicine_2019
650		7	_aHematología _2embne _9140122
650		7	_aTerapia genética _2embne _9150702
700	1		_aPerales, Miguel-Angel. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aAbutalib, Syed A. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _998862
700	1		_aBollard, Catherine. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _9106996
776	0	8	_iPrinted edition: _z9783319543673
776	0	8	_iPrinted edition: _z9783319543697
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-54368-0 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _b02/2023 _eb _zSI