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020			_a9783319935218
024	7		_a10.1007/978-3-319-93521-8 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_aRC918.D53 _b2019 EB
245	0	0	_aDiabetic Nephropathy : _bPathophysiology and Clinical Aspects _cedited by Joris J. Roelofs, Liffert Vogt
264		1	_aCham _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XVI, 548 páginas) _b81 ilustraciones, 67 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_a1. Diabetic nephropathy - Scope of the problem -- Historical overview of diabetic kidney disease -- Clinical features and natural course of diabetic nephropathy -- Global, regional and ethnic differences in diabetic nephropathy -- Diabetic nephropathy in children and adolescents -- Renal disease in obesity, metabolic syndrome and diabesity -- 2. Pathophysiology and clinical pathology of the diabetic kidney -- Introduction to pathogenetic mechanisms of diabetic nephropathy -- The genetics of diabetic nephropathy -- Pathology of the kidney in diabetes -- 3. The glomerulus -- The mesangial cell in diabetic nephropathy -- The glomerular endothelium in diabetic nephropathy - role of heparanase -- The podocyte in diabetic nephropathy: recent advances -- Inflammatory processes in diabetic glomeruli -- 4. The tubulointerstitium -- Proteinuria and tubulotoxicity -- Tubulo-glomerular communication in diabetic nephropathy -- Mechanisms of interstitial fibrosis in diabetic nephropathy -- 5. Microvascular involvement -- Microvascular damage and hemodynamic alterations in diabetic nephropathy -- Coagulation and hemostasis in diabetic nephropathy -- Renal hemodynamics in diabetic kidney disease - relevance for intervention -- Microvascular complications in the eye: diabetic retinopathy -- 6. Macrovascular involvement -- Hypertension in diabetic kidney disease -- Macrovascular involvement in diabetes - renal artery stenosis -- Atherosclerosis and diabetic nephropathy -- 7. Experimental designs -- Animal models of diabetic kidney disease -- Clinical trial and error in diabetic nephropathy -- 8. Therapy of diabetic nephropathy -- Treatment goals in diabetic nephropathy -- Kidney transplantation and diabetic nephropathy -- 9. Future developments -- Health programs in low- and middle-income countries -- OMICs in diabetic kidney disease -- Future and novel compounds in the treatment of diabetic nephropathy.
520	3		_aThis book provides an overview of the most up-to-date research on diabetic nephropathy and the current understanding of its pathogenesis, clinical features and socio-economic developments. Written by leading experts in the field, it provides a comprehensive synthesis of clinical and pathophysiological aspects from a mechanism-based point of view, and reviews evidence-based treatment modalities for the prevention and management of diabetic nephropathy. In addition, closely related areas such as diabesity, diabetic eye disease and macrovascular involvement in diabetes are addressed. Diabetic Nephropathy will be of interest for nephrologists, diabetologists, internists, transplant physicians, public health professionals, basic scientists, geneticists, epidemiologists, pathologists, and molecular and cell biologists working in the field of diabetes and its complications.
988			_aSpringer_Medicine_2019
650		7	_aNefropatías diabéticas _9158639 _2embne
700	1		_aRoelofs, Joris J. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aVogt, Liffert. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _9106996
776	0	8	_iPrinted edition: _z9783319935201
776	0	8	_iPrinted edition: _z9783319935225
776	0	8	_iPrinted edition: _z9783030066789
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-93521-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _b02/2023 _eb _zSI