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008			181003s2019 gw a o |||| 0|eng d
020			_a9783319963648
024	7		_a10.1007/978-3-319-96364-8 _2doi
040			_bspa _cES-MaUEC _dES-MaUEC
050		4	_a RC648 _b2019 EB
245	0	0	_aDisorders of Steroidogenesis : _bGuide to Steroid Profiling and Biochemical Diagnosis _cedited by Gill Rumsby, Gary M. Woodward
264		1	_aCham _bSpringer International Publishing : _bImprint: Springer _c2019
300			_a1 recurso en línea (VIII, 197 páginas 135 ilustraciones, 95 ilustraciones a color)
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aChapter 1: Overview of Adrenal Physiology and Steroid Biochemistry -- Chapter 2: Overview of Adrenocortical Pathophysiology -- Chapter 3: Steroid Profiling - Analytical Perspectives -- Chapter 4: 21-Hydroxylase Deficiency -- Chapter 5: 11β-Hydroxylase deficiency -- Chapter 6: 3b-Hydroxysteroid Dehydrogenase/isomerase Deficiency -- Chapter 7: 17a-Hydroxylase Deficiency -- Chapter 8: Early defects of Steroidogenesis: Steroidogenic acute regulatory protein and cholesterol 20-22 lyase deficiency -- Chapter 9: Aldosterone Synthase Deficiency -- Chapter 10: 17β-Hydroxysteroid Dehydrogenase Deficiency -- Chapter 11: Steroid 5 α-Reductase Deficiency -- Chapter 12: 11β-Hydroxysteroid Dehydrogenase Deficiency -- Chapter 13: Steroid Sulphotransferase and Sulphatase Deficiency -- Chapter 14: Cholesterol Synthesis Defects -- Chapter 15: Steroid Producing Tumours -- Chapter 16: Cushing's syndrome -- Chapter 17: Adrenal insufficiency -- Appendix 1. Common Steroid Identification - GC-MS Mass Spectra.
520	3		_aThis book covers the subject of steroid profiling for the diagnosis of disorders of steroidogenesis. Each chapter provides at least one case study for each of the listed disorders in order to illustrate the subtle and nuanced details required for the diagnosis of these conditions. General information is also given about the biology of these disorders and explanations of typical laboratory findings are provided. This book describes the steroid profile features and its interpretation, in addition to describing the pathophysiology, clinical indications for investigation, general endocrine investigations and genetic considerations for each of the congenital and acquired conditions. A valuable tool for day-to-day clinical and laboratory investigations of adrenal pathologies and disorders of steroidogenesis, as well as providing impetus to further study.
988			_aSpringer_Medicine_2019
650		7	_2embne _9169362 _aGlándulas endocrinas _xEnfermedades
650		7	_2embne _9684920 _aEsteroides
700	1		_aRumsby, Gill. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aWoodward, Gary M. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _9106996
776	0	8	_iPrinted edition: _z9783319963631
776	0	8	_iPrinted edition: _z9783319963655
776	0	8	_iPrinted edition: _z9783030071813
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-96364-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_dz _feng _ggw _h0 _b07/2019 _eh _zSI