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020			_a9789811324024
024	7		_a10.1007/978-981-13-2402-4 _2doi
040			_bspa _dES-MaUEC _cES-MaUEC
050		4	_aRC661 .I63 _b2019 EB
100	1		_aHo, Yvonne _eautor _9670841
245	1	0	_aPatient-specific controller for an implantable artificial pancreas _cby Yvonne Ho
264		1	_aSingapore _bSpringer Singapore : _bImprint: Springer _c2019
300			_a1 recurso en línea (XXII, 84 páginas) _b29 ilustraciones, 19 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aEngineering (Springer-11647)
490	0		_aSpringer Theses Recognizing Outstanding Ph.D. Research _x2190-5053
505	0		_aIntroduction -- Glucose Metabolism and Diabetes -- Literature Review -- Design of an Implantable Artificial Pancreas -- Model Predictive Controller using Interior Point and Ant Algorithm -- In Vivo Experiment of the Implantable Artificial Pancreas -- Parameter Estimation for Nonlinear Mathematical Model -- Conclusion and Future Work.
520	3		_aThe thesis focuses on the control of blood glucose devices and design of implantable devices, and offers valuable insights on diabetes mellitus and related physiology and treatments. Diabetes mellitus is a widespread chronic disease in the modern world that affects millions of people around the globe. In Singapore, one in ten of the population has diabetes, and the severity of the problem has prompted the country's prime minister to talk about the disease at the National Day Rally in 2017. Designing an artificial pancreas that can provide effective blood glucose control for individuals with diabetes is one of the most challenging engineering problems. The author reports on research into the development of an implantable artificial pancreas that can regulate blood glucose levels by delivering appropriate dosages of insulin when necessary. By sensing blood glucose and injecting insulin directly into the vein, the implantable device aims to remove delays that occur with subcutaneous blood glucose sensing and insulin delivery. Preliminary in-vitro and in-vivo experimental results suggest that the implantable device for blood glucose control could be a clinically viable alternative to pancreas transplant.
650		7	_2embne _9138582 _aDiabetes _xTratamiento
650		7	_2embne _9143820 _aIngeniería biomédica
650		7	_2embne _9670731 _aPáncreas _xTrasplante
776	0	8	_iPrinted edition: _z9789811324017
776	0	8	_iPrinted edition: _z9789811324031
776	0	8	_iPrinted edition: _z9789811347702
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-2402-4 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aPrimersemestre_2019_Engineering
998			_aSI _cm _dz _feng _ggw _h0 _b09/2019 _eel _zSI