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020 _a9789811080753
024 7 _a10.1007/978-981-10-8075-3
_2doi
040 _bspa
_dES-MaUEC
_cES-MaUEC
050 4 _aR857 .T55
_b2019 EB
245 0 0 _aMultiscale Mechanobiology in Tissue Engineering
_cDamien Lacroix [y otros siete]
264 1 _aSingapore
_bSpringer Singapore :
_bImprint: Springer
_c2019
300 _a1 recurso en línea (XIII, 203 páginas)
_b102 ilustraciones
336 _2rdacontent
_aTexto
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aEngineering (Springer-11647)
490 0 _aFrontiers of Biomechanics
_x2199-8515
_v3
505 0 _aA review of bioreactors and mechanical stimuli -- Multiscale simulation of bioreactor design and in vitro conditions -- Mechanical stimulation in a PCL additive manufacturing scaffold -- Towards a new approach to analyse quality control and morphometric variability in a scaffold -- Computational simulation of cell seeding in a tissue engineering scaffold -- Collagen gel cell encapsulation to study mechanotransduction -- Collagen gel cell encapsulation to study the effect of fluid flow on mechanotransduction -- Computational modeling of collagen hydrogel -- Mechanical load transfer at the cellular level -- Quantification of CSK mechanics and deformation in relation to cellular functioning -- The future of tissue engineering design for bioreactor stimulation.
520 3 _aThis book focuses on the mechanobiological principles in tissue engineering with a particular emphasis on the multiscale aspects of the translation of mechanical forces from bioreactors down to the cellular level. The book contributes to a better understanding of the design and use of bioreactors for tissue engineering and the use of mechanical loading to optimize in vitro cell culture conditions. It covers experimental and computational approaches and the combination of both to show the benefits that computational modelling can bring to experimentalists when studying in vitro cell culture within a scaffold. With topics from multidisciplinary fields of the life sciences, medicine, and engineering, this work provides a novel approach to the use of engineering tools for the optimization of biological processes and its application to regenerative medicine. The volume is a valuable resource for researchers and graduate students studying mechanobiology and tissue engineering. For undergraduate students it also provides deep insight into tissue engineering and its use in the design of bioreactors. The book is supplemented with extensive references for all chapters to help the reader to progress through the study of each topic.
988 _aPrimersemestre_2019_Engineering
650 7 _2embne
_aTejidos (Biología)
_9668849
650 7 _2embne
_9139084
_aBioingeniería
650 7 _2embne
_aBiotecnología
_9140931
700 1 _aLacroix, Damien
_eautor
_9670241
776 0 8 _iPrinted edition:
_z9789811080746
776 0 8 _iPrinted edition:
_z9789811080760
776 0 8 _iPrinted edition:
_z9789811340567
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-8075-3
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_cm
_dz
_feng
_ggw
_h0
_b08/2019
_eel
_zSI