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336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _9106996
999			_c109394 _d109394 _x1
001			109394
005			20230102113414.0
008			190509s2019 gw | o |||| 0|eng d
020			_a9783030111359
024	7		_a10.1007/978-3-030-11135-9 _2doi
050		4	_aQP356.3
245	0	0	_aIn Vitro Neuronal Networks : _bFrom Culturing Methods to Neuro-Technological Applications _cedited by Michela Chiappalone, Valentina Pasquale, Monica Frega.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XV, 387 páginas) _b102 ilustraciones, 90 ilustraciones a color
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aAdvances in Neurobiology _x2190-5215 _v22
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_a1. Past, present and future of neuronal models in vitro -- 2. In vitro models of neural disorders -- 3. Neuronal cultures and nanomaterials -- 4. Advances in Human Stem Cell Derived Neuronal Cell Culturing and Analysis -- 5. Large scale, high-resolution microelectrode arrays for interrogation of neurons and networks -- 6. Multi-site intracellular recordings -- 7. From MEAs to MOAs: the next generation of bioelectronic interfaces for neuronal cultures -- 8. Scaling spike detection and sorting for next generation electrophysiology -- 9. Burst detection methods -- 10. Reconstruction of functional connectivity from multi-electrode recordings and calcium imaging -- 11. Open-source tools for processing and analysis of in vitro extracellular neuronal signals -- 12. Screening chemicals for potential neurotoxicity and developmental neurotoxicity using neural networks grown on MEAs -- 13. Long-term activity dynamics of single neurons and networks -- 14. Electrical and optical closed-loop systems.
520	3		_aThis book provides a comprehensive overview of the incredible advances achieved in the study of in vitro neuronal networks for use in basic and applied research. These cultures of dissociated neurons offer a perfect trade-off between complex experimental models and theoretical modeling approaches giving new opportunities for experimental design but also providing new challenges in data management and interpretation. Topics include culturing methodologies, neuroengineering techniques, stem cell derived neuronal networks, techniques for measuring network activity, and recent improvements in large-scale data analysis. The book ends with a series of case studies examining potential applications of these technologies.
988			_aPrimersemestre_2019_BiomedLife
650		7	_2embne _aNeurología _9139040
650		7	_2embne _9146728 _aNeuroquímica
700	1		_aChiappalone, Michela. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aFrega, Monica. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _998819
700	1		_aPasquale, Valentina. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030111342
776	0	8	_iPrinted edition: _z9783030111366
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-11135-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b09/2019 _ek _zSI