000			03513nam a22004095i 4500
003			ESmaUEC
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
040			_aES-MaUEC _bspa _cES-MaUEC
336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _9106996
999			_c109382 _d109382 _x1
001			109382
005			20230102113413.0
008			190604s2019 si | o |||| 0|eng d
020			_a9789811366017
024	7		_a10.1007/978-981-13-6601-7 _2doi
050		4	_aQP551 _b2019 EB
100	1		_aKurochkina, Natalya _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _993900
245	1	0	_aProtein Structure and Modeling _cby Natalya Kurochkina.
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VIII, 274 páginas) _b76 ilustraciones, 60 ilustraciones a color
337			_aelectrónico _bc
338			_arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aProtein Structure -- Conformational transitions -- Allosteric regulation -- Protein channels -- Helical assemblies -- Multiprotein complexes -- Methods of structure determination -- Protein modeling -- References -- Dictionary.
520	3		_aThe volume covers the advances made by the most recent experimental and theoretical research in the structure of the most extensively studied main biological macromolecules - the proteins. Proteins are remarkably regular highly ordered biopolymers. Their precise organization allows living organisms to reliably perform complex functions. The book features an introduction into methods of protein structure determination, design, and modeling, and addresses the structural principles of fibrous and globular proteins such as enzymes, channels, signaling molecules and adaptors, and the relationships between primary, secondary, tertiary, and quaternary structure. The main focus is on determinants of protein conformation, canonical and noncanonical amino acids and polypeptides, conformational states and transitions, structure elements and arrangements, protein folds, helical assemblies, multiprotein complexes, structure and function relationships, the specificity of molecular recognition, ligand binding, and involvement in cellular processes. The book is a must read for scientists, engineers, teachers, undergraduate and graduate students, business professionals, and curious learners in the fields of Life Sciences and Biomedical Research. Prof. Natalya Kurochkina heads The School of Theoretical Modeling, Washington, DC, USA, teaches, and conducts research. She has PhD in Biophysics, from the Institute of Protein Research, Russian Academy of Sciences and worked as a postdoctoral fellow at the National Cancer Institute of the National Institute of Health. Her research focuses on principles of protein structure and protein conformation, and determinants of specificity of molecular recognition.
988			_aPrimersemestre_2019_BiomedLife
650		7	_2embne _aProteínas _xEstructura _9669891
650		7	_2embne _aBioquímica _9138639
776	0	8	_iPrinted edition: _z9789811366000
776	0	8	_iPrinted edition: _z9789811366024
776	0	8	_iPrinted edition: _z9789811366031
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-6601-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b09/2019 _ek _zSI