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336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _9106996
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005			20230102113412.0
008			190603s2019 si | o |||| 0|eng d
020			_a9789811316043
024	7		_a10.1007/978-981-13-1604-3 _2doi
050		4	_aQH506 _b2019 EB
245	0	0	_aMolecular Diagnostics : _bPart 1 : Technical Backgrounds and Quality Aspects _cedited by E. van Pelt-Verkuil, W.B. van Leeuwen, R. te Witt
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (VII, 457 páginas) _b224 ilustraciones, 205 ilustraciones a color
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aThe importance of nucleic acids in diagnostics -- Background and analysis of nucleic acids -- Primers and probes -- Basic principles of nucleic acid hybridisation -- Principles of PCR -- Quality assurance, management and control in molecular diagnostics -- Quantitative isothermal molecular amplification techniques -- DNA sequencing -- Bioinformatics -- The ongoing revolution of MALDI TOF Mass Spectrometry for Molecular Diagnostics -- Information in the amplification curve.
520	3		_aThe books Molecular Diagnostics Part 1 and 2 provide a comprehensive and practical overview of the state-of-the-art molecular biological diagnostic strategies that are being used in a wide variety of disciplines. The editors and experts in their respective fields have combined their knowledge to write these two books. Many years of experience in the development, application and quality control of molecular diagnostic methods is reflected herewith. Molecular Diagnostics Part 1 is dedicated to the theoretical backgrounds of the technologies often applied in molecular diagnostics, in which nucleic acid amplification methods (such as real-time PCR), sequencing and bioinformatics are the basic tools. The assay design and -development, combined with items of trouble-shooting are described in detail. As a foundation of reliable molecular diagnostic assays, the quality control required for validation, implementation and performance of molecular diagnostic assays is thoroughly discussed. This book also provides extensive information for those working with molecular techniques in a wide variety of research applications using conventional and real-time PCR technology, Sanger and high throughput sequencing techniques, and bioinformatics. Molecular Diagnostics Part 2 highlights the applications of the molecular diagnostic methods in the various diagnostic laboratories, comprising: - Clinical microbiology - Clinical chemistry - Clinical genetics - Clinical pathology - Molecular hematopathology - Veterinary health - Plant health - Food safety Both full-color and well-illustrated books are particularly valuable for students, clinicians, scientists and other professionals who are interested in (designing) molecular diagnostic methods and for those who wish to broaden their knowledge on the current molecular biological revolution. The information in the books highlights the trend of the integration of multiple (clinical) disciplines into one universal molecular laboratory. .
988			_aPrimersemestre_2019_BiomedLife
650		7	_2embne _aBiología molecular _9139103
650		7	_2embne _aPatología _9138489
700	1		_ate Witt, R. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_avan Leeuwen, W.B. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_avan Pelt-Verkuil, E. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9789811316036
776	0	8	_iPrinted edition: _z9789811316050
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-1604-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b08/2019 _ek _zSI