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040			_aES-MaUEC _bspa _cES-MaUEC
336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _9106996
999			_c109345 _d109345 _x1
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005			20230102113411.0
008			190327s2019 gw | s |||| 0|eng d
020			_a9783030126681
024	7		_a10.1007/978-3-030-12668-1 _2doi
050		4	_aRC627.54 _b2019 EB
245	0	0	_aReviews on Biomarker Studies of Metabolic and Metabolism-Related Disorders _cedited by Paul C. Guest.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XI, 303 páginas) _b39 ilustraciones, 22 ilustraciones a color
337			_aelectrónico _bc
338			_arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
490	0		_aProteomics Metabolomics Interactomics and Systems Biology ; _v1134
505	0		_a1. Insulin Resistance in Schizophrenia -- 2. Biogenesis of the Insulin Secretory Granule in Health and Disease -- 3. Current Models of Fatty Liver Disease; New Insights, Therapeutic Targets and Interventions -- 4. Preclinical Models of Altered Early Life Nutrition and Development of Reproductive Disorders in Female Offspring -- 5. Targeting Mitochondrial Defects to Increase Lngevity in Animal Models of Neurodegenerative Diseases -- 6. Computational Approaches for Identification of Pleiotropic Biomarker Profiles in Psychiatry -- 7. MiRNA Regulation of Glucose and Lipid Metabolism in Relation to Diabetes and Non-Alcoholic Fatty Liver Disease -- 8. Hypercaloric Diet-Induced Obesity and Obesity-Related Metabolic Disorders in Experimental Models -- 9. Metabolic Biomarkers in Nematode C. elegans During Aging -- 10. Circular RNAs as potential biomarkers and therapeutic targets for metabolic diseases -- 11. Deciphering Endothelial Dysfunction in the HIV-Infected Population -- 12. The Role of Inflammation in the Development of GDM and The Use of Markers of Inflammation in GDM Screening -- 13. PFKP Signaling at a Glance: an Emerging Mediator of Cancer Cell Metabolism -- 14. ATAD3A on the Path to Cancer -- 15. Impact of Exercise on Inflammatory Mediators of Metabolic and Vascular Insulin Resistance in Type 2 Diabetes.
520	3		_aThe book recognizes that throughout the scientific, medical, and economic communities, new tests incorporating biomarkers are needed to improve the diagnosis of patients suffering from metabolic disorders. The early identification of those at risk of developing obesity will help to place these individuals on the best treatment course as early as possible for improved treatment outcomes. This will also help to cut costs incurred by the healthcare services. For all of this to occur, new research efforts are needed to identify novel biomarkers that can be used to predict the disease in the presymptomatic stage, for disease monitoring and for prediction of treatment response. It is also possible that new drug targets can be identified using these approaches which, in turn, can lead to the development of new treatment approaches. This volume also includes a series of reviews on biomarker discovery and usage in the study of diseases marked by perturbations in metabolism. It will describe the pros and cons of the various approaches and cover the successes and failures in this important research field.
988			_aPrimersemestre_2019_BiomedLife
650		7	_2embne _aMetabolismo _xTrastornos _9168790
650		7	_2embne _aMarcadores biológicos _9162047
700	1		_aGuest, Paul C. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783030126674
776	0	8	_iPrinted edition: _z9783030126698
776	0	8	_iPrinted edition: _z9783030126704
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-030-12668-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b08/2019 _ek _zSI