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040			_aES-MaUEC _bspa _cES-MaUEC
336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _9106996
999			_c109315 _d109315 _x1
001			109315
005			20230102113409.0
008			190313s2019 si | o |||| 0|eng d
020			_a9789811329777
024	7		_a10.1007/978-981-13-2977-7 _2doi
050		4	_aRB112.5 _b2019 EB
245	0	0	_aHuman Pathobiochemistry : _bFrom Clinical Studies to Molecular Mechanisms _cedited by Toshitaka Oohashi, Hirokazu Tsukahara, Francesco Ramirez, Chad L. Barber, Fumio Otsuka.
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XI, 349 páginas) _b167 ilustraciones, 113 ilustraciones a color
337			_aelectrónico _bc
338			_arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPart1. Metabolic Disorders -- 1. Citrin Deficiency -- 2. Aspartoacylase Deficiency (Canavan Disease, N-Acetylaspartic Aciduria) -- 3. Prominent Insulin Resistance in Congenital Generalized Lipoatrophy -- 4. Fabry Disease -- 5. Familial Hypercholesterolemia -- 6. Gaucher Disease -- 7. Heme Oxygenase-1 Deficiency -- 8. The Homocystinurias -- 9. Hypophosphatasia -- 10. Phenylketonuria -- 11. Triglyceride Deposit Cardiomyovasculopathy -- 12. Urea Cycle Disorders -- 13. Wilson Disease -- Part2. Genetics -- 14. Achondroplasia -- 15. Acute Myeloid Leukemia: Mutations Blocking Differentiation Lead to Distinct Leukemic Subtypes -- 16. α1-Antitrypsin Deficiency -- 17. Hereditary Anticoagulant Deficiencies -- 18. Cherubism -- 19. Cancer and Excess Iron -- 20. Fukuyama Congenital Muscular Dystrophy and Related Diseases -- 21. Hereditary Proteinuric Glomerular Disorders -- 22. Marfan Syndrome -- 23. When Materials Are at Fault: The Skeletal Collagens, Osteogenesis Imperfecta and Chondrodysplasias -- Part3. Others -- 24. Acute Kidney Injury: Transition to Chronic Kidney Disease -- 25. Type I Interferonopathies: Common Pathological Features Between Congenital Infections and Genetic Disorders -- 26. Epilepsy -- 27. Hemophagocytic Lymphohistiocytosis -- 28. Hepatitis C Virus Infection -- 29. Substance Abuse Emergencies.
520	3		_aThis textbook uses a case-study approach to present the core principles of biochemistry and molecular biology in the context of human disease to students who will be involved in patient care. The 29 clinical cases have been carefully selected to cover key scientific concepts and some common, and other not so common, diseases. While the principal focus is on topics relating to metabolic disease, further subjects such as connective tissue disorders, neurological disorders, auto-inflammatory disorders, infective diseases, and cancer are also addressed. Each chapter provides a specific patient report that includes the natural history, pertinent clinical laboratory data, physical findings, subsequent diagnosis, and therapy. This is followed by a comprehensive discussion of the normal biochemical processes and reactions pertaining to the case, along with the pathophysiological mechanisms of the disease. Graphical diagrams are provided in each chapter for ease of comprehension.
988			_aPrimersemestre_2019_BiomedLife
650		7	_2embne _aBioquímica clínica _9149316
650		7	_2embne _aFisiología humana _9140024
700	1		_aBarber, Chad L. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aOohashi, Toshitaka. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aOtsuka, Fumio. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aRamirez, Francesco. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aTsukahara, Hirokazu. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _985013
776	0	8	_iPrinted edition: _z9789811329760
776	0	8	_iPrinted edition: _z9789811329784
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-2977-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b08/2019 _ek _zSI