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020 _a9789811361982
024 7 _a10.1007/978-981-13-6198-2
_2doi
050 4 _aRC268.57
_b2019 EB
245 0 0 _aVirus Infection and Tumorigenesis :
_bHints from Marine Hosts' Stress Responses
_cedited by Xiaobo Zhang.
264 1 _aSingapore
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (V, 318 páginas)
_b8 ilustraciones, 7 ilustraciones a color
337 _aelectrónico
_bc
338 _arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aOverview of virus infection and tumorigenesis -- Marine viruses -- Marine invertebrate stress responses to virus infection -- The roles of microRNAs in antiviral immunity of marine invertebrates -- Marine microbe stress responses to bacteriophage infection -- Roles of microbial metabolites in bacteriophage-microbe interactions -- Tumorigenesis and metabolism disorder -- Effects of microRNAs from marine invertebrate stress responses to virus infection on tumorigenesis -- Anti-tumor activities of secondary metabolites from marine microbe stress responses to virus infection.
520 3 _aThis book reviews the latest research on the molecules and mechanisms of marine host stress responses to viral infections and tumorigenesis. It offers an overview of the state of the art in the field as well as future directions. Metabolism disorder is a characteristic of tumorigenesis. Since viruses complete their life cycle in host cells, such infections cause metabolic disorders in the host. As such, the mechanisms of virus pathogenesis and tumor progression are similar or even identical. In essence, the role of antiviral molecules is to maintain the metabolic homeostasis of infected host cells, and the antiviral molecules induced by virus infection may play an important role in antitumor pathways, resulting in cancer cell death or restoring the disordered metabolism of cancer cells. The molecules generated during host stress responses to viruses can also contribute to the antitumor mechanisms in humans. However, the relationship between host stress responses to virus infection and tumorigenesis has not been extensively explored. In recent years, studies have shown that marine host stress responses to viral invasion can be good models for exploring human antitumor mechanisms. Stimulating further research in the field, this book offers graduate students and researchers with comprehensive insights into host stress responses to viral invasion and tumor progression. It is also a valuable resource for those working in the pharmaceutical industry interested in drug discovery based on molecules derived from host stress responses to viral infection.
988 _aPrimersemestre_2019_BiomedLife
650 7 _2embne
_9670226
_aCarcinogénesis viral
650 7 _2embne
_9413643
_aVirología médica
700 1 _aZhang, Xiaobo.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9789811361975
776 0 8 _iPrinted edition:
_z9789811361999
776 0 8 _iPrinted edition:
_z9789811362002
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-6198-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_cm
_dz
_feng
_ggw
_h0
_b08/2019
_ek
_zSI