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336 _aTexto
_btxt
_2rdacontent
988 _aSpringerBiomedLife_2019
999 _c109245
_d109245
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020 _a9783030055424
024 7 _a10.1007/978-3-030-05542-4
_2doi
050 4 _aR853.B54
_b2019 EB
245 0 0 _aReviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
_cedited by Paul C. Guest.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2019
300 _a1 recurso en línea (XIII, 328 páginas)
_b28 ilustraciones, 26 ilustraciones a color
337 _aelectrónico
_bc
338 _arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
490 0 _aProteomics Metabolomics Interactomics and Systems Biology ;
_v1118
505 0 _a1. The Potential of 'Omics to Link Lipid Metabolism and Genetic and Comorbidity Risk Factors of Alzheimer's Disease in African Americans -- 2. The Role of Biomarkers in Alzheimer's Disease Drug Development -- 3. Mitochondrial Involvement in Mental Disorders; Energy Metabolism, Genetic and Environmental Factors -- 4. Lymphocytes, Platelets, Erythrocytes and Exosomes as Possible Biomarkers for Alzheimer's Disease Clinical Diagnosis -- 5. Genetic Risk Factors for Alzheimer Disease: Emerging Roles of Microglia in Disease Pathomechanisms -- 6. Neuroimaging Studies of Cognitive Function in Schizophrenia -- 7. The Role of Biomarkers in Psychiatry -- 8. Interactome Studies of Psychiatric Disorders -- 9. MicroRNAs in Major Depressive Disorder -- 10. Proteomic Markers for Depression -- 11. Advances in Biomarker Studies in Autism Spectrum Disorders -- 12. Proteomic Investigations of Autism Spectrum Disorder: Past Findings, Current Challenges and Future Prospects -- 13. Role of the Gut Microbiome in Autism Spectrum Disorders -- 14. Metabolomic Biomarkers in Mental Disorders: Bipolar Disorder and Schizophrenia -- 15. Early Detection and Treatment of Patients with Alzheimer's Disease: Future Perspectives.
520 3 _aThis book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.
650 7 _2embne
_aMarcadores biológicos
_9162047
650 7 _2embne
_9162770
_aExpresión génica
700 1 _aGuest, Paul C.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
776 0 8 _iPrinted edition:
_z9783030055417
776 0 8 _iPrinted edition:
_z9783030055431
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi-org/10.1007/978-3-030-05542-4
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_cm
_dz
_feng
_ggw
_h0
_b07/2019
_ek
_zSI