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040			_aES-MaUEC _bspa _cES-MaUEC
336			_aTexto _btxt _2rdacontent
988			_aSpringerBiomedLife_2019
999			_c109226 _d109226 _x1
001			109226
005			20230110040215.0
008			190124s2019 si | o |||| 0|eng d
020			_a9789811336331
024	7		_a10.1007/978-981-13-3633-1 _2doi
050		4	_aQL391.N4 _b2019 EB
100	1		_aWang, Dayong _eautor _9669903
245	1	0	_aMolecular Toxicology in Caenorhabditis elegans _cby Dayong Wang.
264		1	_aSingapore _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XVIII, 447 páginas) _b285 ilustraciones, 211 ilustraciones a color
337			_aelectrónico _bc
338			_arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aMolecular Basis for Oxidative Stress Induced by Environmental Toxicants in Nematodes -- Molecular Basis for Reduced Lifespan Induced by Environmental Toxicants or Stresses -- Roles of Oxidative Stress Related Molecular Signals in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of MAPK Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of Insulin and the Related Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of Development Related Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of Cell Death and DNA Damage Related Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of Metabolism Related Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of Protective Response Related Signalling Pathways in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Functions of G-Protein Coupled Receptors and Ion Channels and the Downstream Cytoplasmic Signals in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Discussion on Specificity of Molecular Signals in Response to Certain Environmental Toxicants or Stresses -- Epigenetic Regulation of Toxicity of Environmental Toxicants or Stresses -- Strategies to Screen and to Identify New Genetic Loci Involved in the Regulation of Toxicity of Environmental Toxicants or Stresses -- Molecular Basis for Adaptive Response to Environmental Toxicants or Stresses -- Molecular Basis for Transgenerational Toxicity Induction of Environmental Toxicants or Stresses.
520	3		_aThis book will focus on the molecular basis of oxidative stress induced by toxicants or stresses and various molecular signalling pathways in regulating the toxicity of toxicants or stresses in Caenorhabditis elegans. It will also cover the discussion on the aspects of response signals, G-protein coupled receptors and ion channels, specific molecular signals, and epigenetic signals involved in the regulation of toxicity from toxicants or stresses. The molecular basis for adaptive response for transgenerational toxicity of environmental toxicants or stresses will be further discussed. Nematode Caenorhabditis elegans is a classic model animal with well-described genetic and developmental backgrounds based on the study of life science, and has been further successfully and widely used in both toxicity assessment and toxicological study of various environmental toxicants or stresses. Based on related available data, this book aims at providing a systematic understanding of the knowledge system of molecular toxicology in C. elegans.
650		7	_2embne _9138758 _aInvertebrados
650		7	_2embne _aCitología _9139477
776	0	8	_iPrinted edition: _z9789811336324
776	0	8	_iPrinted edition: _z9789811336348
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi-org/10.1007/978-981-13-3633-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b07/2019 _ek _zSI