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336			_aTexto _btxt _2rdacontent
988			_aSpringerBiomedLife_2019
999			_c109211 _d109211 _x1
001			109211
005			20230110040215.0
008			190523s2019 gw | o |||| 0|eng d
020			_a9783030151386
024	7		_a10.1007/978-3-030-15138-6 _2doi
050		4	_aQR201.H44 _b2019 EB
245	0	0	_aMolecular Mechanisms of Inflammation : _bInduction, Resolution and Escape by Helicobacter pylori _cedited by Steffen Backert
264		1	_aCham, Switzerland _bSpringer International Publishing _c2019
300			_a1 recurso en línea (XXIV, 359 páginas) _b29 ilustraciones, 28 ilustraciones a color
337			_aelectrónico _bc _2rdamedia
338			_arecurso electrónico _bcr _2rdacarrier
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
490	0		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v421
505	0		_aInflammation, immunity and vaccine development for the gastric pathogen Helicobacter pylori -- Impact of Helicobacter pylori Virulence Factors on the Host immune Response and Gastric Pathology -- Genetic polymorphisms in inflammatory and other regulators in gastric cancer: risks and clinical consequences -- MALT lymphoma as a model of chronic inflammation-induced gastric tumor development -- Crosstalk between DNA damage and inflammation in the multiple steps of gastric carcinogenesis -- Importance of toll-like receptors in pro-inflammatory and anti-inflammatory responses by Helicobacter pylori infection -- Role of NOD1 and ALPK1/TIFA signalling in innate immunity against Helicobacter pylori infection -- Carbohydrate-dependent and antimicrobial peptide defense mechanisms against Helicobacter pylori infections -- The sweeping role of cholesterol depletion in the persistence of Helicobacter pylori infections -- Helicobacter pylori deregulates T and B cell signaling to trigger immune evasion -- Mechanisms of inflammasome signaling, microRNA induction and resolution of inflammation by Helicobacter pylori -- Impact of the gastrointestinal microbiome in health and disease: co-evolution with the host immune system -- Resolution of gastric cancer-promoting inflammation: a novel strategy for anti-cancer therapy.
520	3		_aThis book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world's population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection. This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.
650		7	_2embne _9150368 _aInfecciones por Helicobacter pylori
650		7	_2embne _aGastroenterología _9141308
700	1		_aBackert, Steffen. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _999785
776	0	8	_iPrinted edition: _z9783030151379
776	0	8	_iPrinted edition: _z9783030151393
776	0	8	_iPrinted edition: _z9783030151409
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi-org/10.1007/978-3-030-15138-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _cm _dz _feng _ggw _h0 _b07/2019 _ek _zSI