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008 171115s2018 gw | s |||| 0|eng d
020 _a9783319690599
_9
024 7 _a10.1007/978-3-319-69059-9
_2doi
040 _aES-MaUEC
_bspa
050 4 _aRC350 2018 EB
100 1 _aTay, Andy Kah Ping
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aAcute and Chronic Neural Stimulation via Mechano-Sensitive Ion Channels
_cby Andy Kah Ping Tay.
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2018.
300 _a1 recurso en línea (XVII, 119 páginas 33 ilustraciones, 32 ilustraciones a color)
347 _atext file
_bPDF
_2rda
490 0 _aSpringer Theses, Recognizing Outstanding Ph.D. Research,
_x2190-5053
505 0 _aMicro- and Nano-Technologies to Probe Brain Mechanobiology -- Acute Neural Stimulation -- Chronic Neural Stimulation -- Phenotypic Selection of Magnetospirillum magneticum (AMB-1) Over-Producers using Magnetic Ratcheting -- Magnetic Microfluidic Separation for Estimating the Magnetic Contents of Magnetotactic Bacteria -- Outlook for Magnetic Neural Stimulation Techniques.
520 _aThis book describes the tools, developed by the author, for perturbing endogenous mechano-sensitive ion channels for magneto-mechanical neuro-modulation. He explores the ways in which these tools compare against existing ones such as electricity, chemicals, optogenetics, and techniques like thermos/magneto-genetics. The author also reports on two platforms—magnetic ratcheting and magnetic microfluidics for directed evolution and high throughput culture of magnetotactic bacteria—that produce high quality magnetic nanoparticles for biomedical applications like neural stimulations. This thesis was submitted to and approved by the University of California, Los Angeles. Introduces technology for non-invasive control of neural activities that offer deep tissue penetration and controllable dosage; Examines the effects of biomechanical forces on cellular functions; Explores how to improve the reproducibility and uptake of magnetic tools for non-invasive neural modulation.
650 7 _aNeuroestimulación
_9158566
_2embne
650 7 _aNanotecnología
_2embne
_9158453
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iPrinted edition:
_z9783319690582
776 0 8 _iPrinted edition:
_z9783319690605
776 0 8 _iPrinted edition:
_z9783319887081
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-69059-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aEngineering (Springer-11647)
998 _b03/2019
_dz
_ep
_feng
_ggw
_h0
999 _c108070
_d108070