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999			_c107012 _d107012
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003			ESmaUEC
005			20230102113323.0
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007			cr nn nnnaamaa
008			181229s2018 gw | s |||| 0|eng d
020			_a9783319995465
024	7		_a10.1007/978-3-319-99546-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP801.C27 _b2018 EB
100	1		_aBöttger, Angelika _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9685350
245	1	0	_aLessons on Caffeine, Cannabis & Co : _bPlant-derived Drugs and their Interaction with Human Receptors _cby Angelika Böttger, Ute Vothknecht, Cordelia Bolle, Alexander Wolf
264		1	_aCham _bSpringer International Publishing _c2018
300			_a1 recurso en línea (X, 217 páginas) _b69 ilustraciones, 50 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aLearning Materials in Biosciences _x2509-6125
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aIntroduction: Plant secondary metabolites and their general function in plants -- Historical and current perspective -- Medicinal use -- Recreational use -- General overview over biosynthesis pathways of plant secondary metabolites -- Drugs affecting GPCR: GPCRs in plants and animals -- Dopamine and 5-HT2A-serotonin receptors - Cocaine, mescaline, psilobin -- Opiate receptors - morphine, salvinorin A -- Cannabinoid receptors - THC -- Muscarinergic acetylcholin receptor - muscarin, atropine -- Adenosine receptor - caffeine -- Drugs affecting ion channels: Ligand and voltage activated channels -- Nicotinic acetylcholin receptor - Nicotine, Curare -- GABAA/C-receptor - Muscimol, thujone -- ionotropic Glycine receptor - Strychnine -- ionotropic Glutamate receptor - ibogtenic acid, kainic acid -- TRP channels - capsaicin, menthol, aconitine, resiniferatoxin -- Anti-cancer drugs acting on the cell cycle: Cell cycle in animals and plants -- Microtubuli - Colchicine, taxol, vinblastine, Podophyllotoxin (Lignan) -- Topoisomerase - camptothecin, etoposide -- G2/M phase arrest, apoptosis - curcubitacin, triptolide.
520	3		_aThis textbook provides a structured, easy to understand and thorough insight into the mode of function of plant secondary metabolites in plants and humans. It explains the biosynthesis and molecular action of nicotine, cannabis, caffeine and Co, describes the effects of these drugs on signal transduction at receptors and ion channels in animals, their relevance for human health and their potential for recreational use and abuse. It also offers a broad and comprehensive understanding on the role and function of these diverse molecules for the plants that make them. This textbook is written for master students and scientist in biochemistry and biology as well as for pharmaceutical and medical students. It will be a valuable study tool for teachers and students alike.
650		7	_aCannabis _2embne _9147710 _xEfectos fisiológicos
650		7	_aCafeína _2embne _9682820 _xEfectos fisiológicos
700	1		_aVothknecht, Ute _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9685351
700	1		_aBolle, Cordelia _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _9685352
700	1		_aWolf, Alexander _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n91054941 _9685353 _c(Of Helmholtz Zentrum München)
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _9106996
776	0	8	_iPrinted edition: _z9783319995458
776	0	8	_iPrinted edition: _z9783319995472
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-99546-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
988			_aEBSPRINGER_BIOMEDLIFE_2019
998			_aSI _aSI _aSI _b06/2019 _cm _dz _feng _ggw _h0 _eIG _zSI