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336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
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020			_a9783319996646
024	7		_a10.1007/978-3-319-99664-6 _2doi
050		4	_aQR46 _b2018 EB
245	1	0	_aEscherichia coli, a Versatile Pathogen _cedited by Gad Frankel, Eliora Z Ron.
264		1	_aCham _bSpringer International Publishing _c2018
300			_a1 recurso en línea (VII, 242 páginas 40 ilustraciones, 20 ilustraciones a color)
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aCurrent Topics in Microbiology and Immunology _x0070-217X _v416
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aShigella and enteroinvasive Escherichia coli -- Enteroaggregative Escherichia coli -- The Type III Secretion System of pathogenic Escherichia coli -- Modulation of host cell processes by T3SS effectors -- The 2011 German enterohemorrhagic Escherichia coli O104:H4 outbreak - the danger is still out there -- Extraintestinal Pathogenic Escherichia coli -- Pandemic bacteremic Escherichia coli strains: evolution and emergence of drug resistant pathogens -- Current Trends in Antimicrobial Resistance of Escherichia coli -- Vaccines against Escherichia coli.
520	3		_aEscherichia coli is a facultative anaerobic Gamma-proteobacterium, which belongs to the family Enterobacteriaceae. While being an important constituent of the normal gut microbiota, specialized E. coli clones have acquired genetic elements that allow them to compete with the endogenous commensals, colonise normally sterile niches and cause disease. E. coli pathotypes can cause intestinal and extra intestinal infections (e.g. UTI, sepsis) and associate with mammalian cells while being extra- or intra-cellular. In recent years, E. coli infections have become a serious clinical problem, due to the rapid spread of antibiotic resistance. Thus, infections with intestinal E. coli (e.g. E. coli O104) or extraintestinal pathogenic strains (e.g. E. coli ST131) are becoming difficult to treat and are often lethal. Consequently, there is a pressing need to develop alternative control measures, including the identification of new drug targets and development of vaccines that offer lasting protection. This volume focuses on several types of E. coli infections (intestinal and extraintestinal), virulence factors, and E. coli pandemics. It addresses the problem of antibiotic resistance, and a dedicated chapter discusses the need to develop alternative control measures. Given its depth and breadth of coverage, the book will benefit all those interested in the biology, genetics, physiology and pathogenesis of E. coli, and in related vaccine development.
988			_aEBSPRINGER_BIOMEDLIFE_2019
650		7	_9405049 _aMicrobiología médica _2
700	1		_aFrankel, Gad _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2018024949 _1http://viaf.org/viaf/141152079183807112045
700	1		_aRon, Eliora Z _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/58212419
776	0	8	_iPrinted edition: _z9783319996639
776	0	8	_iPrinted edition: _z9783319996653
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-99664-6 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _aSI _aSI _b06/2019 _cm _dz _feng _ggw _h0 _eIG _zSI