000			04977nam a22003975i 4500
003			ESmaUEC
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
040			_aES-MaUEC _bspa _cES-MaUEC
336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
999			_c106950 _d106950 _x1
001			106950
005			20230102113320.0
008			181130s2018 gw | s |||| 0|eng d
020			_a9783319995939
024	7		_a10.1007/978-3-319-99593-9 _2doi
050		4	_aRS380 _b2018 EB
245	0	0	_aADME Processes in Pharmaceutical Sciences : _bDosage, Design, and Pharmacotherapy Success _cedited by Alan Talevi, Pablo A. M. Quiroga
264		1	_aCham _bSpringer International Publishing _c2018
300			_a1 recurso en línea (X, 362 páginas) _b88 ilustraciones, 67 ilustraciones a color
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aPart 1 The Basics of ADME Processes -- Introduction ADME Processes and Their Relationship with Pharmaceutical Practice -- Drug Release -- Drug Adsorption -- Drug Excretion.-Routes of Administration -- Part 2 The Importance of ADME Properties in Burgeoning Pharmaceutical Topics -- Nanotechnology and Drug Delivery -- Pharmacogenomics and Indiviualized Therapy -- Bioavailability and Bioequivalence Studies -- The Absorption and Distribution of Biopharmaceuticals/Biological Medical Products -- Drug-Drug and Food-Drug Interactions of Pharmacokinetic Nature -- In silico and In vitro ADME prediction -- Drug Transporters and Multi-drug Resistance.
520	3		_aAbsorption, Distribution, Metabolism and Excretion (ADME) processes and their relationship with the design of dosage forms and the success of pharmacotherapy form the basis of this upper level undergraduate/graduate textbook. As an introduction oriented to pharmacy students, it is also written for scientist from different fields outside of pharmaceutics. (e.g. material scientist, material engineers, medicinal chemists) who might be working in a positions in pharmaceutical companies or whose work might benefit from basic training in the ADME concepts and some biological background. Pedagogical features such as objectives, keywords, discussion questions, summaries and case studies add valuable teaching tools. This book will provide not only general knowledge on ADME processes but also an updated insight on some hot topics such as drug transporters, multi-drug resistance related to pharmacokinetic phenomena, last generation pharmaceutical carriers (nanopharmaceuticals), in vitro and in vivo bioequivalence studies, biopharmaceuticals, pharmacogenomics, drug-drug and food-drug interactions, and in silico and in vitro prediction of ADME properties. In comparison with other similar textbooks, around half of the volume would be focused on the relationship between expanding scientific fields and ADME processes. Each of these burgeoning fields has a separate chapter in the second part of the volume, and was written with leading experts on the correspondent topic, including scientists and academics from USA and UK (Duquesne University School of Pharmacy, Indiana University School of Medicine, University of Utah College of Pharmacy, University of Maryland, University of Bath). Additionally, each of the initial chapters dealing with the generalities of drug absorption, distribution, metabolism and excretion would include relevant, classic examples related to each topic with appropriate illustrations (e.g. importance of active absorption of levodopa, implications in levodopa administration, drug drug interactions and food drug interactions emerging from the active uptake; intoxication with paracetamol as a result of glutathione depletion, CYP induction and its relationship with acute liver failure caused by paracetamol, etc). ADME Processes and Pharmaceutical Sciences is written as a core textbook for ADME processes, pharmacy, pharmacokinetics, drug delivery, biopharmaceutics, drug disposition, drug design and medicinal chemistry courses.
988			_aEBSPRINGER_BIOMEDLIFE_2019
650		7	_9155839 _aBiotecnología farmacéutica _2
700	1		_aTalevi, Alan _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n2017181975 _1http://viaf.org/viaf/6075148997650259870002
700	1		_aQuiroga, Pablo A. M _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iPrinted edition: _z9783319995922
776	0	8	_iPrinted edition: _z9783319995946
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-99593-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _aSI _aSI _b06/2019 _cm _dz _feng _ggw _h0 _eIG _zSI