000			03039nam a22003975i 4500
001			106901
003			ESmaUEC
005			20230102113318.0
006			a||||fo|||| 00| 0
007			cr nn nnnaamaa
008			181119s2018 si | s |||| 0|eng d
020			_a9789811315718 _9
024	7		_a10.1007/978-981-13-1571-8 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP552.G16 _b2018 EB
100	1		_aRajagopal, Senthilkumar _eautor _9668852
245	1	0	_aMetabotropic GPCRs : _bTGR5 and P2Y Receptors in Health and Diseases _cby Senthilkumar Rajagopal, Murugavel Ponnusamy
264		1	_aSingapore _bSpringer Singapore _c2018
300			_a1 recurso en línea (XII, 76 páginas) _b27 ilustraciones, 20 ilustraciones a color
336			_aTexto _btxt _2rdacontent
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF _2rda
505	0		_aModule 1. Overview of G-Protein coupled receptor -- Module 2. TGR5 receptor -- Module 3. P2Y receptor -- Module 4. Therapeutically Targeting TGR5 & P2Y receptors. .
520	3		_aThis book will provide current understandings about two ubiquitously expressed metabotropic GPCRs, G-coupled purinoreceptor type 2 (P2Y) and Takeda G-protein-coupled bile acid receptor 5 (TGR5). G protein coupled receptors (GPCRs) are the largest family of proteins implicated in majority of cellular responses. The two receptor sub-families play a central role in many physiological functions as well as in many pathological conditions. This book offers up-to-date information on the physiological functions, signaling pathways and regulatory mechanisms of P2Y and TGR5 receptors. In addition, this book provides a comprehensive overview about the abnormalities of P2Y/TGR5 receptors and their contribution in the development and progression of pathological conditions. It also covers the currently available natural, chemical and pharmacological agents targeting these two receptor families and their therapeutic implications in P2Y and TGR5 associated disorders. This book is a valuable source for beginners and researchers to follow the rapidly progressing field of these two GPCR subfamily members.
650		7	_aProteínas G _2embne _9147588
700	1		_aPonnusamy, Murugavel _e. _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2018184189 _1http://viaf.org/viaf/81152742959927731683
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iPrinted edition: _z9789811315701
776	0	8	_iPrinted edition: _z9789811315725
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-1571-8 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_BIOMEDLIFE_2019
998			_aSI _a_alco _a_vill _b01/2019 _cm _dz _ef _feng _ggw _h0
999			_c106901 _d106901 _x1