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020 _a9783319895062
_9
024 7 _a10.1007/978-3-319-89506-2
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aQP552.N39
_b2018 EB
245 0 0 _aTextbook of Energy Balance, Neuropeptide Hormones, and Neuroendocrine Function
_cedited by Eduardo A. Nillni
264 1 _aCham
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XIV, 378 páginas)
_b49 ilustraciones, 47 ilustraciones a color
336 _aTexto
_btxt
_2rdacontent
347 _atext file
_bPDF
_2rda
505 0 _a1. The Evolution from Lean to Obese State and the Influence of Modern Human Society -- 2. Neuropeptides Controlling Our Behavior -- 3. Transcriptional Regulation of Hypothalamic Energy Balance Genes -- 4. Brain Inflammation and Endoplasmic Reticulum Stress -- 5. The Cell Biology of Neuropeptide Hormones -- 6. Nutrient Sensors Regulating Peptides -- 7. Gatrointestinal Hormones Controlling Energy Homeostasis and Their Potential Role in Obesity -- 8. The Complexity of Adipose Tissue -- 9. Adipokines, Inflammation and Insulin Resistance in Obesity -- 10. The Thyroid Hormone Axis: Its Roles in Body Weight Regulation, Obesity and Weight Loss -- 11. Obesity and Stress: The Melanocortin Connection -- 12. Obesity and the Growth Hormone Axis -- 13. Brain, Environment, Hormone-Based in of Appetite, Ingestive Behavior, and Body Weight.
520 3 _aThis textbook presents for the first time a comprehensive body of the latest knowledge in the field of neuropeptides and their action on energy balance. It contains a detailed and comprehensive account of the specific hypothalamic peptides in regards to their roles in energy balance, food intake control and co-morbidities, to better understand the patho-physiology of obesity. The textbook includes an examination the history of the evolution of human society from a thin to the obese phenotype and, within that context, how modern society habits and industrial food production did not respect the evolutionary trait resulting in changes in the energy balance set point. It provides a novel conceptualization of the problem of obesity when considering the biochemistry of peptide hormones and entertaining novel ideas on multiple approaches to the problems of energy balance, as well as demonstrates and explains why alterations in pro-hormone processing are paramount to understand metabolic disease. This text is excellent material for teaching graduate and medical school courses, as well as a valuable resource for researchers in biochemistry, cell, and molecular biology, neuroscientists, physician endocrinologists, and nutritionists.
650 7 _aNeuropéptidos
_9502304
_2embne
650 7 _aNeuroendocrinología
_9141862
_2embne
700 1 _aNillni, Eduardo A
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iPrinted edition:
_z9783319895055
776 0 8 _iPrinted edition:
_z9783319895079
776 0 8 _iPrinted edition:
_z9783030077877
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-89506-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aBiomedical and Life Sciences (Springer-11642)
942 _2lcc
988 _aEBSPRINGER_BIOMEDLIFE_2019
998 _aSI
_a_alco
_a_vill
_b01/2019
_cm
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999 _c106855
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