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008			180404s2018 si | s |||| 0|eng d
020			_a9789811084881 _9
024	7		_a10.1007/978-981-10-8488-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP364.7 _b2018 EB
245	0	0	_aNicotinic Acetylcholine Receptor Signaling in Neuroprotection _cedited by Akinori Akaike, Shun Shimohama, Yoshimi Misu
264		1	_aSingapore _bSpringer Singapore _c2018
300			_a1 recurso en línea (X, 191 páginas) _b62 ilustraciones, 24 ilustraciones a color
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2rda
505	0		_a1.Overview -- 2.In vivo imaging of nicotinic acetylcholine receptors in the central nervous system -- 3.A new aspect of cholinergic transmission in the central nervous system -- 4.Nicotinic acetylcholine receptor signaling: roles in neuroprotection -- 5.Regulation by nicotinic acetylcholine receptors of microglial glutamate transporters: role of microglia in neuroprotection -- 6.Shati/Nat8l and N-acetylaspartate (NAA) have important roles in regulating nicotinic acetylcholine receptors in neuronal and psychiatric diseases in animal models and humans -- 7.Nicotinic acetylcholine receptors in regulation of pathology of cerebrovascular disorders -- 8.Roles of nicotinic acetylcholine receptors in the pathology and treatment of Alzheimer's and Parkinson's diseases -- 9.SAK3-induced neuroprotection is mediated by nicotinic acetylcholine receptors -- 10.Removal of blood amyloid as a therapeutic strategy for Alzheimer's disease: the influence of smoking and nicotine.
506	0		_aOpen Access
520	3		_aThis open access book presents the roles and mechanisms of signal transduction triggered by nicotinic acetylcholine receptors (nAChRs) stimulation in neuroprotection against toxic effects of risk factors of neurodegenerative diseases. Accumulating evidence suggests that nAChRs in the CNS play important roles not only in excitatory neurotransmission but also in neuronal survival and related functions. Neuroprotection mediated by nAChRs in neurodegenerative diseases such as Alzheimer's disease is the major topic of this book. In response to rapidly evolving areas in clinical and laboratory neuropharmacology and neurochemistry, this volume provides in-depth coverage of neuroprotection in basic research and future developments in the clinical application of effective neuroprotective strategies in neurodegenerative diseases. This work appeals to both basic and clinical researchers in several fields, such as neuroscience, neurology, and pharmacology. This book is published with open access under a CC BY 4.0 license.
650		7	_aReceptores de neurotransmisores _2embne _9159080
700	1		_aAkaike, Akinori _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/16009883
700	1		_aShimohama, Shun _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n2018189560 _1http://viaf.org/viaf/5154620869444591964
700	1		_aMisu, Yoshimi _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/11395255
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iPrinted edition: _z9789811084874
776	0	8	_iPrinted edition: _z9789811084898
776	0	8	_iPrinted edition: _z9789811341663
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-8488-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_BIOMEDLIFE_2019
998			_aSI _a_alco _a_vill _b01/2019 _cm _dz _ef _feng _ggw _h0
999			_c106853 _d106853 _x1