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008			181102s2018 si | s |||| 0|eng d
020			_a9789811312861 _9
024	7		_a10.1007/978-981-13-1286-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP171 _b2018 EB
245	0	0	_aNeural Regulation of Metabolism _cedited by Qi Wu, Ruimao Zheng
264		1	_aSingapore _bSpringer Singapore _c2018
300			_a1 recurso en línea (XI, 233 páginas) _b30 ilustraciones, 21 ilustraciones a color
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2rda
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1090
505	0		_aFunctional interrogation of the AgRP neural circuits in control of appetite, body weight, and behaviors -- The Leptin Signalings -- The Leptin Resistance -- Neuronal cAMP/PKA Signaling and Energy Homeostasis -- POMC neurons feeding and reward -- Synaptic Regulation of Metabolism -- Glial Regulation of Energy Metabolism -- Regulation of Lipolysis in Adipose Tissue and Clinical Significance -- Electrophysiological mechanism of peripheral hormones and nutrients regulating energy homeostasis -- Central Circadian Clock Regulates Energy Metabolism -- Ghrelin signaling in immunometabolism and inflamm-aging -- Current genetic techniques in neural circuit control of feeding and energy metabolism.
520	3		_aThis book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural regulation of metabolism is a central mechanism that controls metabolic status physiologically and pathophysiologically. The book first introduces the latest studies on the neural and cellular mechanisms of hypothalamic neurons, hypothalamic glial cells, neural circuitries, cellular signaling pathways, and synaptic plasticity in the control of appetite, body weight, feeding-related behaviors and metabolic disorders. It then summarizes the humoral mechanisms by which critical adipocyte-derived hormones and lipoprotein lipase regulate lipid and glucose metabolism, and examines the role of the hypothalamus-sympathetic nerve, a critical nerve pathway from CNS to peripheral nervous system (PNS), in the regulation of metabolism in multiple tissues/organs. Furthermore, the book discusses the functions of adipose tissue in energy metabolism. Lastly, it explores dietary interventions to treat neural diseases and some of the emerging technologies used to study the neural regulation of metabolism. Presenting cutting-edge developments in the neural regulation of metabolism, the book is a valuable reference resource for graduate students and researchers in the field of neuroscience and metabolism.
650		7	_aMetabolismo _2embne _9138638
700	1		_aWu, Qi _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/n82062193 _1http://viaf.org/viaf/60435064
700	1		_aZheng, Ruimao _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/no2019011466 _1http://viaf.org/viaf/19154865963159942553
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iPrinted edition: _z9789811312854
776	0	8	_iPrinted edition: _z9789811312878
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-1286-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_BIOMEDLIFE_2019
998			_aSI _a_alco _a_vill _b01/2019 _cm _dz _ef _feng _ggw _h0
999			_c106835 _d106835 _x1