000 03378nam a22004215i 4500
988 _aSpringer_Medicine_2018
999 _c106672
_d106672
_x1
001 106672
003 DE-He213
005 20230102113311.0
006 a||||fo|||| 00| 0
007 cr nn 008mamaa
008 180929s2018 gw | s |||| 0|eng d
020 _a9783319614212
024 7 _a10.1007/978-3-319-61421-2
_2doi
040 _bspa
_dES-MaUEC
_cES-MaUEC
050 4 _aRC645.7
_b2018 EB
245 0 0 _aBone Marrow Failure
_cedited by Gary M. Kupfer, Gregory H. Reaman, Franklin O. Smith
264 1 _aCham
_bSpringer International Publishing :
_bImprint: Springer
_c2018.
300 _a1 recurso en línea (IX, 214 páginas, 19 ilustraciones, 12 ilustraciones a color)
336 _2rdacontent
_aTexto (visual)
_btxt
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
_2rda
490 0 _aPediatric Oncology,
_x1613-5318
490 0 _aMedicine (Springer-11650)
505 0 _a1. The Cellular and Molecular Mechanisms of Hematopoiesis -- 2. Acquired Aplastic Anemia -- 3. Pediatric Myelodysplastic Syndromes -- 4. Fanconi Anemia: A Pathway of Hematopoeisis and Cancer Predisposition -- 5. Ribosomopathies Through a Diamond Lens -- 6. Dyskeratosis Congenita and the Telomere Biology Disorders -- 7. Diamond Blackfan Anemia -- 8. Shwachman-Diamond Syndrome -- 9. Hematopoietic Cell Transplantation for the Treatment of Patients with Bone Marrow Failure Syndromes -- 10. Inherited Neutropenias and Their Insights into Cellular and Developmental Biology -- 11. Inherited Thrombocytopenias.
520 _aThis book presents the latest scientific knowledge on inherited and acquired bone marrow failure syndromes, describing the advances in understanding of genetics and pathophysiology that have been achieved as a result of high-throughput DNA sequencing, RNA expression studies, and modern biochemistry techniques. The full range of relevant conditions is covered, including acquired aplastic anemia, Fanconi anemia, ribosomopathies, telomeropathies, dyskeratosis congenita, Shwachman-Diamond syndrome, Diamond-Blackfan anemia, and congenital neutropenias and thrombocytopenias. In addition, it is explained how the study of these rare diseases has uncovered important new science and elucidated the pathophysiology of more common hematological and oncological diseases. A treatment-specific chapter describes options ranging from the conventional to the cutting edge. Bone Marrow Failure will be of value for both trainee and practicing hematologists and oncologists.
650 7 _2embne
_9519857
_aMédula ósea
_xEnfermedades
700 1 _aKupfer, Gary M.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aReaman, Gregory H.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988773
700 1 _aSmith, Franklin O.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_988772
710 2 _aSpringerLink (Online service)
_9106996
776 0 8 _iPrinted edition:
_z9783319614205
776 0 8 _iPrinted edition:
_z9783319614229
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-61421-2
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _b06/2019
_dz
_feng
_ggw
_h0
_ea