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008 141010s2015 xxk| s |||| 0|eng d
020 _a9781447165996
024 7 _a10.1007/978-1-4471-6599-6
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aTA342 2015 EB
245 1 0 _aMultiscale Modeling in Biomechanics and Mechanobiology
_cedited by Suvranu De, Wonmuk Hwang, Ellen Kuhl.
264 1 _aLondon
_bSpringer International Publishing
_c2015
300 _a1 recurso en línea (VIII, 286 páginas 84 ilustraciones, 63 ilustraciones a color.)
505 0 _a1. Proteins: Ssp DnaE Intein -- 2. Protein Crystals: Molecular to Continuum Level Models based on Crystal Plasticity Theory -- 3. Molecular Motors: Cooperative Phenomena of Multiple Molecular Motors. - 4. Biofilament dynamics: Line-to-rod-level Descriptions -- 5. Primary Cilia: Multi-Scale Structures that integrate Biomechanics and Mechanobiology. - 6. Biological Scaffolding: Reduced-Order Network Models -- 7. Transport phenomena: Computational models for convective and diffusive transport in capillaries and tissue -- 8.Tendons and ligaments: Current state and future directions. - 9. Arteries: Mechanics, Mechanobiology, and the Need for a New Class of Models -- 10. Mitral Valves: A computational framework. - 11. Biological systems: Multiscale modeling based on Mixture Theory.
520 3 _aPresenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models.   Biomechanics involves the study of the interactions of physical forces with biological systems at all scales - including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces - bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines.   Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.
650 7 _aModelado multiescala
_9669485
_2embne
650 7 _aBiomecánica
_xModelos matemáticos
_9669486
_2embne
700 1 _aDe, Suvranu.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_1http://viaf.org/viaf/120550843/
700 1 _aHwang, Wonmuk.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/no2014158925
_1http://viaf.org/viaf/311784692/
700 1 _aKuhl, Ellen.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/n2007050909
_1http://viaf.org/viaf/262954556/
776 0 8 _iEdición impresa:
_z9781447166009
776 0 8 _iEdición impresa:
_z9781447165989
776 0 8 _iEdición impresa:
_z9781447172291
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-1-4471-6599-6
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aEngineering (Springer-11647)
988 _aEBSPRINGER_2018
998 _b06/2019
_dz
_ek
_feng
_ggw
_h0
999 _c104009
_d104009
_x1