000			03574nam a22003615i 4500
001			102974
003			DE-He213
005			20230102113108.0
007			cr nn 008mamaa
008			180110s2018 ja | s |||| 0|eng d
020			_a9784431565147
024	7		_a10.1007/978-4-431-56514-7 _2doi
050		4	_aQP88.2 2018 EB
040			_aES-MaUEC _bspa
100	1		_aKameo, Yoshitaka _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2018185474 _1http://viaf.org/viaf/103153409679441581067/
245	1	0	_aBone Adaptation _bIn Silico Approach _cby Yoshitaka Kameo, Ken-ichi Tsubota, Taiji Adachi.
264		1	_aTokyo _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XIV, 209 páginas 93 ilustraciones, 24 ilustraciones a color)
347			_atext file _bPDF
490	0		_aFrontiers of Biomechanics _x2199-8515 _v2
505	0		_aOverview: In Silico Approaches to Understand Bone Adaptation -- Microscopic Fluid Flow Analysis in an Osteocyte Canaliculus -- Macroscopic Fluid Flow Analysis in a Poroelastic Trabecula -- Estimation of Bone Permeability for Poroelastic Analysis -- Modeling Trabecular Bone Adaptation Induced by Flow Stimuli to Osteocytes -- Effects of Local Bending Load on Trabecular Bone Adaptation -- Cancellous Bone Adaptation Predicted by Remodeling Simulations -- Trabecular Surface Remodeling toward Uniform Local Stress State -- Spatial and Temporal Regulation of Cancellous Bone Structure by Trabecular Surface Remodeling -- Comparison of Mechanical Quantities as Bone Remodeling Stimuli -- Trabecular Surface Remodeling Simulation of Cancellous Bone Using Image-Based Voxel Finite Element Models -- Functional Adaptation of Cancellous Bone in Human Proximal Femur -- 3D Trabecular Remodeling in Human Proximal Femur: Approach to Understanding Wolff's Law -- Trabecular Structural Changes in a Vertebral Body with a Fixation Screw.
520	3		_aThis book focuses on the systems biomechanics of bone remodeling that provide a multiscale platform for bone adaptation, spanning the cellular, tissue, and organ levels. The mathematical model explained in each section provides concrete examples of in silico approaches for bone adaptation. It will be immensely useful for readers interested in bone morphology and metabolism and will serve as an effective bridge connecting mechanics, cellular and molecular biology, and medical sciences. These in silico approaches towards exploring the mechanisms by which the functioning of dynamic living systems is established and maintained have potential for facilitating the efforts of graduate students and young researchers pioneering new frontiers of biomechanics.
650		7	_9666561 _aHuesos _2embne
700	1		_aTsubota, Ken-ichi _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2018186519 _1http://viaf.org/viaf/117153409692541580774/
700	1		_aAdachi, Taiji _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2015185500 _1http://viaf.org/viaf/253924767/
776	0	8	_iEdición impresa: _z9784431565123
776	0	8	_iEdición impresa: _z9784431565130
776	0	8	_iEdición impresa: _z9784431568087
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-4-431-56514-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aEngineering (Springer-11647)
988			_aEBSPRINGER_2018
998			_b02/2019 _dz _ef _feng _ggw _h0
999			_c102974 _d102974 _x1