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020 _a9783319676098
024 7 _a10.1007/978-3-319-67609-8
_2doi
050 4 _aRS201.N35
_bM365 2018 EB
100 1 _aManisekaran, Ravichandran
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 0 _aDesign and Evaluation of Plasmonic/Magnetic Au-MFe2O4 (M-Fe/Co/Mn) Core-Shell Nanoparticles Functionalized with Doxorubicin for Cancer Therapeutics
_cby Ravichandran Manisekaran.
264 1 _aCham
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XL, 168 páginas 91 ilustraciones, 84 ilustraciones a color.)
347 _atext file
_bPDF
490 0 _aSpringer Theses, Recognizing Outstanding Ph.D. Research
_x2190-5053
505 0 _aIntroduction to Nanomedicine and Cancer Therapy -- Literature Survey on Magnetic, Gold and Core-Shell Nanoparticles -- Characterization Techniques, Cell Cultivation and Experimental Setup -- Designing a Nanocargo with Fe3O4@Au: A Tri-pronged Mechanism for MR Imaging, Synaphic Drug-delivery and Apoptosis Induction in Cancer Cells -- Multiple Iterative Seeding of Surface Plasmon Enhanced Cobalt-Iron Oxide Nanokernels for Cancer Theranostics -- Nano-flotillas MnFe2O4@Au Core-shell Nanoparticles: An Efficient MRI Contrast Agent, Magneto-hyperthermal and Drug-delivery Armada for Cancer -- Concluding Remarks and Future Prospects.
520 3 _aThis thesis documents the development of a multifunctional nanoparticle system to enhance the chemotherapeutic efficiency of anti-cancer drugs, and contributes to research that helps decrease the side-effects in cancer patients while simultaneously increasing their survival rates. The work begins with an introduction to nanomedicine and cancer therapy, and contains a literature review on magnetic, gold, and core-shell nanoparticles. It also covers synthesis techniques, properties, various surface modifications, and the importance of magnetic and gold nanoparticles. The author dedicates a chapter to characterization techniques, experimental setup, and cell cultivation techniques for in-vitro studies. Further chapters describe the background, characterizations, and applications of multifunctional magnetite coated gold core-shell nanoparticles, and the doping of cobalt to magnetite and manganese to magnetite nanoparticles. The important highlight of this research was the control of the size, shape, composition, and surface chemistry of nanoparticles.
650 7 _aIngeniería biomédica
_9143820
650 7 _aNanotecnología
_2embne
_9158453
776 0 8 _iEdición impresa:
_z9783319676081
776 0 8 _iEdición impresa:
_z9783319676104
776 0 8 _iEdición impresa:
_z9783319884578
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-67609-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aEngineering (Springer-11647)
988 _aEBSPRINGER_2018
998 _b01/2019
_dz
_ea
_feng
_ggw
_h0
999 _c102861
_d102861
_x1