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020 _a9783319747750
024 7 _a10.1007/978-3-319-74775-0
_2doi
040 _aES-MaUEC
_bspa
050 4 _aQ342
_b2018 EB
100 1 _aJana, Nanda Dulal
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
245 1 2 _aA Metaheuristic Approach to Protein Structure Prediction
_bAlgorithms and Insights from Fitness Landscape Analysis
_cby Nanda Dulal Jana, Swagatam Das, Jaya Sil.
264 1 _aCham
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XXIX, 220 páginas 59 ilustraciones, 54 ilustraciones a color)
347 _atext file
_bPDF
490 0 _aEmergence, Complexity and Computation
_x2194-7287
_v31
505 0 _aMetaheuristic Protein Structure Prediction-An Overview -- Related Works -- Continuous Landscape Analysis using Random Walk Algorithm -- Landscape Characterization and Algorithms Selection for the PSP Problem -- The Levy distributed Parameter Adaptive Metaheuristic Algorithm for Protein Structure Prediction -- Protein Structure Prediction using Improved Variants of Metaheuristic Algorithms -- Hybrid Metaheuristic Approach for Protein Structure Prediction -- Conclusions and Future Research.
520 3 _aThis book introduces characteristic features of the protein structure prediction (PSP) problem. It focuses on systematic selection and improvement of the most appropriate metaheuristic algorithm to solve the problem based on a fitness landscape analysis, rather than on the nature of the problem, which was the focus of methodologies in the past. Protein structure prediction is concerned with the question of how to determine the three-dimensional structure of a protein from its primary sequence. Recently a number of successful metaheuristic algorithms have been developed to determine the native structure, which plays an important role in medicine, drug design, and disease prediction. This interdisciplinary book consolidates the concepts most relevant to protein structure prediction (PSP) through global non-convex optimization. It is intended for graduate students from fields such as computer science, engineering, bioinformatics and as a reference for researchers and practitioners.
650 7 _9666321
_aIngeniería asistida por ordenador
650 7 _aInteligencia artificial
_2embne
_9413115
650 7 _aBioquímica
_2embne
_9138639
700 1 _aDas, Swagatam
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_0http://id.loc.gov/authorities/names/nb2009009215
_1http://viaf.org/viaf/86100097/
_998976
700 1 _aSil, Jaya
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_1http://dbpedia.org/resource/Jaya_Seal
776 0 8 _iEdición impresa:
_z9783319747743
776 0 8 _iEdición impresa:
_z9783319747767
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-74775-0
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aEngineering (Springer-11647)
988 _aEBSPRINGER_2018
998 _b12/2018
_dz
_ea
_feng
_ggw
_h0
999 _c102072
_d102072
_x1