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336			_aTexto _btxt _2rdacontent
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
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008			180703s2018 gw | s |||| 0|eng d
020			_a9783319772585
024	7		_a10.1007/978-3-319-77258-5 _2doi
050		4	_aRC157 _b2018 EB
245	1	0	_aComplement Activation in Malaria Immunity and Pathogenesis _cedited by José A. Stoute.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XII, 149 páginas 22 ilustraciones,17 ilustraciones a color)
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aBiomedical and Life Sciences (Springer-11642)
505	0		_aThe Complement System -- Mechanisms of Complement Activation in Malaria -- Role of Complement in Severe Malarial Anemia -- Role of Complement in Cerebral Malaria -- Role of Complement in Placental Malaria -- Complement Evasion Mechanisms of the Human Pathogen Plasmodium falciparum -- Role of Complement in Immunity Against Malaria -- Complement-like System in the Mosquito Responses Against Malaria Parasites.
520	3		_aPlasmodium falciparum malaria is responsible for the deaths of nearly 500,000 people each year. Much attention has been paid to antibody and cellular mechanisms of immunity against this pathogen. By contrast, the role that the complement system plays in immunity and pathogenesis in this infection is not very well recognized or understood. Based on the work of a number of research groups, we know that complement plays an important role in these processes. In this book, some of the leading scientists in the field discuss the mechanisms of complement activation during malaria infection as well as the role of complement in the pathogenesis of key syndromes such as severe malarial anemia, cerebral malaria, and placental malaria. In addition, they review recently-identified complement evasion strategies of P. falciparum merozoites, and how these mechanisms may translate into paradoxical enhancement of infection rather than protection. Finally, they also discuss the role of the mosquito complement system on immunity against the parasite. .
650		7	_aInmunología _2embne _9138330
650		7	_aParasitología médica _2embne _9405319
650		7	_aEnfermedades infecciosas _2embne _9138404
700	1		_aStoute, José A _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
776	0	8	_iEdición impresa: _z9783319772578
776	0	8	_iEdición impresa: _z9783319772592
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-77258-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE
998			_aSI _b03/2019 _cm _dz _ep _feng _ggw _h0