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336 _aTexto
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_2rdacontent
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
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020 _a9789811075308
024 7 _a10.1007/978-981-10-7530-8
_2doi
050 4 _aRC564
_b2018 EB
100 1 _aLi, Ming D.
_eautor
_4aut
_4http://id.loc.gov/vocabulary/relators/aut
_0http://id.loc.gov/authorities/names/nb2016002808
_1http://viaf.org/viaf/149145541831696601803
245 1 0 _aTobacco Smoking Addiction: Epidemiology, Genetics, Mechanisms, and Treatment
_cby Ming D. Li.
264 1 _aSingapore
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XIII, 365 páginas 44 ilustraciones,33 ilustraciones a color)
337 _2rdamedia
_aelectrónico
_bc
338 _2rdacarrier
_arecurso electrónico
_bcr
347 _atext file
_bPDF
490 0 _aBiomedical and Life Sciences (Springer-11642)
505 0 _aThe Prevalence of Smoking and Its Associated Diseases.- Addiction Genetics: Basic Concepts and Techniques.- Estimation of Genetic and Environmental Contributions to Smoking Addiction -- Identified Susceptibility Loci for Nicotine Addiction Based on Genome-Wide Linkage Analyses -- Involvement of Variants in Gene Clusters CHRNA5/A3/B4 on Chromosome 15 to Smoking Behaviors and Lung Cancer.- Contribution of Variants in CHRNB3/A6 Gene Cluster on Chromosome 8 to Smoking Dependence.- Genetic Contribution of Variants in GABAergic Signaling to Nicotine Dependence.- Contribution of Variants in DRD2/ANKK1 on Chromosome 11 with Smoking and Other Addictions.- Significant Contribution of Variants in Serotonin Transporter and Receptor Genes to Smoking Dependence.- Converging Findings from Linkage and Association Analyses on Susceptibility Genes for Smoking Addiction.- Contribution of Gene-Gene and Gene-Environmental Interactions to Tobacco Smoking.- Identification of Biological Pathways Associated with Smoking Initiation/Progression, Nicotine Dependence, and Smoking Cessation.- Neuroproteomics and Its Applications in Research on Nicotine and Other Drugs of Abuse.- Regulatory Roles of MicroRNAs in Addictions and Other Psychiatric Diseases.- Tobacco Smoking, Food Intake, and Weight Control.- Nicotine Modulates Innate Immune Pathways via α7 Nicotinic Acetylcholine Receptor.- DNA Methylation Analysis Reveals a Strong Connection between Tobacco Smoking and Cancer Pathogenesis.- Evolutionary Relations of Genes Encoding Nicotinic Acetylcholine Receptor Subunits.- Management, Pharmacotherapies, and Precision Medicine for Smoking Cessation.- Background and Biology of and Health Concerns about Electronic Cigarettes.- Grand Challenges and Opportunities for Psychiatry, Including Nicotine Addiction Research.
520 3 _aThis book provides the most recent knowledge on almost all key aspects of the health impact of tobacco smoking.  Its 21 chapters focus on both preclinical and clinical studies. The contents are broad, covering the epidemiology of tobacco smoking; genetic epidemiology; identification of susceptibility genomic regions, genes, and pathways as determined by both human and animal studies; evolutionary relations among the different nAChR subunit genes that are so important to the nicotine response; smoking-related diseases; E-cigarettes; and smoking cessation. Furthermore, each chapter includes a detailed and comprehensive list of key references.  For both clinical and basic researchers, this book is a valuable resource on nicotine dependence and other addictions.
650 7 _aTabaco
_2embne
_xEfectos fisiológicos
_9405938
650 7 _aPsiquiatría
_2embne
_9139041
650 7 _aToxicología
_2embne
_9140328
776 0 8 _iEdición impresa:
_z9789811075292
776 0 8 _iEdición impresa:
_z9789811075315
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-10-7530-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942 _2lcc
_cLE
998 _aSI
_b03/2019
_cm
_dz
_ep
_feng
_ggw
_h0