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020 _a9783319727998
_9
024 7 _a10.1007/978-3-319-72799-8
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aQR46 2018 EB
245 1 0 _aUpdates on Clostridium difficile in Europe :
_bAdvances in Microbiology, Infectious Diseases and Public Health Volume 8
_cedited by Paola Mastrantonio, Maja Rupnik.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (VIII, 261 páginas 25 ilustraciones,16 ilustraciones a color)
336 _aTexto
_btxt
_2rdacontent
347 _atext file
_bPDF
_2
490 0 _aAdvances in Microbiology, Infectious Diseases and Public Health
_x2365-2675
_v1050
505 0 _aForeword (P. Mastrantonio and M. Rupnik) -- Economic burden of CDI in European countries (E. Reigadas and E. Bouza) -- The need for European surveillance of CDI(C. Wiuff, A.Lan Banks, F. Fitzpatrick, L. Cottom) -- Diagnostic guidance for C. difficile infections (M.J.T. Crobach,A.Baktash, N. Duszenko, E.J. Kuijper) -- Ribotypes and new virulent strains across Europe (J. Couturier, K. Davies, C. Gateau, F. Barbut) -- Comparative genomics of C. difficile strains (S. Janezic, J.R.Garneau, M. Monot) -- Cellular uptake and mode-of-action of Clostridium difficile toxins (P.Papatheodorou, H. Barth, N. Minton, K. Aktories) -- Clostridium difficile biofilm (C. Vuotto, G. Donelli, A. Buckley, C. Chilton) -- European practice for CDI treatment (F. Fitzpatrick, M. Skally, M. Brady, K. Burns, C. Rooney, M.H. Wilcox) -- Antibiotic resistances of Clostridium difficile (P. Spigaglia, P. Mastrantonio, F. Barbanti) -- Probiotics for prevention and treatment of Clostridium difficile infection (L. Valdés-Varela, M. Gueimonde, P. Ruas-Madiedo) -- Faecal microbiota transplantation as emerging treatment in European countries (M. Maida, J. McIlroy, G. Ianiro, G. Cammarota) -- Immunization strategies against Clostridium difficile (J.F. Bruxelle, S. Péchiné, A. Collignon) -- Non-human C. difficile reservoirs and sources: animals, food, environment (C. Rodriguez Diaz, C. Seyboldt , M. Rupnik) -- The ESCMIDStudy Group for Clostridium difficile: history, role and perspectives (J.E. Coia and E.J. Kuijper).
520 3 _aThis book outlines the currently available clinical, epidemiological and experimental data on Clostridium difficile infection (CDI) with special emphasis on studies and results achieved in Europe. The incidence and severity of CDI has increased significantly over the last decade, and the book explains why C. difficile, recently reclassified as Clostridioides difficile, remains a significant challenge, also from economic perspective, to health care systems all over the world. The different reservoirs of this ubiquitous microorganism are reviewed as well as the different factors contributing to its virulence, such as toxins and biofilm formation. The rapid evolution of antibiotic resistance is clearly a concern and in a specific way can influence the CDI epidemiology. Additionally, new emerging strains and comparative genomics studies are discussed for their relevance from epidemiological and evolutionary point of view. The book also gives an overview on diagnostics, therapy and surveillance, all of which are still challenging. Therefore, a closer look is taken on the effect of probiotics as an alternative to antibiotics, for prevention and treatment of CDI. Fecal transplantation from healthy donors, passive immunotherapies and vaccines for patients with recurrences are also discussed in dedicated chapters. The book closes with a summary of the history and the achievements of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Clostridium difficile (ESGCD) written by the current and past presidents of the Society. It is the aim of this book to raise awareness on CDI and to disseminate updated information on its prevention, diagnosis and treatment.
650 7 _aMicrobiología
_2embne
_9138684
650 7 _aEnfermedades infecciosas
_2embne
_9138404
700 1 _aMastrantonio, Paola
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/no2018056524
_1http://viaf.org/viaf/12152561635915442960
700 1 _aRupnik, Maja
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/no2018056458
_1http://viaf.org/viaf/25152561532515440322
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9783319727981
776 0 8 _iEdición impresa:
_z9783319728001
776 0 8 _iEdición impresa:
_z9783319892108
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-72799-8
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aBiomedical and Life Sciences (Springer-11642)
942 _2lcc
988 _aEBSPRINGER_2018
998 _aSI
_b02/2019
_cm
_dz
_ep
_feng
_ggw
_h0
999 _c100947
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