000			03335nam a22003735i 4500
001			100919
003			ESmaUEC
005			20230102113017.0
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007			cr nn nnnaamaa
008			180625s2018 gw | s |||| 0|eng d
020			_a9783319712321 _9
024	7		_a10.1007/978-3-319-71232-1 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQR46
245	1	0	_aBiology of Chlamydia _cedited by Georg Häcker.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (X, 237 páginas)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aCurrent Topics in Microbiology and Immunology, _x0070-217X _v412
505	0		_aCell wall biosynthesis in Chlamydia -- Genetic manipulation in Chlamydia --  Early events in the Chlamydia developmental cycle --  Subversion of the host cell cytoskeleton by Chlamydia -- Cell-autonomous host defence against Chlamydia infection -- The enigma of long-term infection: are there quiescent or 'persistent' Chlamydia?- Mechanisms of immunopathogenesis during chlamydial infections -- Protective adaptive immune response and prospects for a vaccine -- The hidden genomics of Chlamydia trachomatis.
520	3		_aThe genus Chlamydia encompasses a number of species of obligate intracellular bacteria, including important human pathogens like the most common bacterial agent of sexually transmitted disease. This volume reviews current knowledge of chlamydial biology, covering the unusual structure of the bacteria - which alternate between metabolically almost inactive and fast-dividing forms. It also discusses the ways in which Chlamydia manipulates the host cytoskeleton and subverts the host cell's defence, and illustrates how genomics have begun to uncover the diversity and complexity of chlamydial strains that look very similar but may cause distinct forms of disease. Further, it describes how techniques are now finally being established that can genetically modify Chlamydia, and discusses why such modification is still very difficult and what progress we can expect. Lastly, it presents our current understanding of chlamydial disease: what do we know about chronic infections, what are the mechanisms of inflammatory damage, and what are the prospects of a vaccine? Written be specialists in these various areas, the book is a valuable work of reference for students and scientists with an interest in the molecular, cellular and immunobiology of these fascinating bacteria.
650		7	_aMicrobiología _2embne _9138684
650		7	_aEnfermedades infecciosas _2embne _9138404
700	1		_aHäcker, Georg. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2018016396
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319712307
776	0	8	_iEdición impresa: _z9783319712314
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-71232-1 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_2018
999			_c100919 _d100919 _x1