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008			180622s2018 gw | s |||| 0|eng d
020			_a9783319926339 _9
024	7		_a10.1007/978-3-319-92633-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aR154.F655 2018 EB
100	1		_aRibatti, Domenico _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _1http://viaf.org/viaf/102495071 _986304
245	1	0	_aJudah Folkman : _bA Biography _cby Domenico Ribatti.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (VIII, 124 páginas 29 ilustraciones,16 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
505	0		_aBiographic profile -- Development of assays to study angiogenesis -- Tumor angiogenesis -- The discovery of angiogenic factors -- Anti-angiogenesis -- Concluding remarks -- References -- Publications of Judah Folkman (2014-1956). Index.
520	3		_aThe aim if this book is to analyze the scientific biography of Judah Folkman, one of the most important scientist of the last century. More 50 years ago, Folkman found a revolutionary new way to think about cancer. Blood supply, Folkman hypothesized, was the key to tumor growth. Without new blood vessels, tumors simply did not thrive. In 1971, Folkman published his theory of angiogenesis in the "New England Journal of Medicine". Angiogenesis, the formation and recruitment of new blood vessels, is necessary for tumor growth. Critics of the theory were silenced over time as Folkman and his colleagues reported the first purified angiogenic molecule, the first angiogenesis inhibitor and proposed the concept of angiogenic disease. The mechanism of angiogenesis is now a worldwide field of investigation. Over the years, Folkman and a growing team of researchers have isolated the proteins and unraveled the processes that regulate angiogenesis. Meanwhile, a new generation of angiogenesis research has emerged as well, widening the field into new areas of human disease and deepening it to examine the underlying biological processes responsible for those diseases.
650		7	_aMedicina _2embne _9405021
650		7	_aCitología _2embne _9139477
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319926322
776	0	8	_iEdición impresa: _z9783319926346
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-92633-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_2018
998			_aSI _b02/2019 _cm _dz _ep _feng _ggw _h0
999			_c100905 _d100905 _x1