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007			cr nn nnnaamaa
008			180612s2018 gw | s |||| 0|eng d
020			_a9783319901497 _9
024	7		_a10.1007/978-3-319-90149-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aRB155 2018 EB
245	1	4	_aThe Genetics and Development of Scoliosis _cedited by Kenro Kusumi, Sally L. Dunwoodie.
250			_a2nd edition
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XII, 199 páginas 29 ilustraciones,12 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
505	0		_aChapter1: Developmental and Functional Anatomy of the Spine -- Chapter2: Environmental Factors and Axial Skeletal Dysmorphogenesis -- Chapter3: Congenital Scoliosis and Segmentation Defects of the Vertebrae in the Genetic Clinic -- Chapter4: The Genetics Contributing to Disorders involving Congenital Scoliosis -- Chapter5: Animal Models of Idiopathic Scoliosis -- Chapter6: Current Understanding of Genetic Factors in Idiopathic Scoliosis -- Chapter7: Genetics and Functional Pathology of Idiopathic Scoliosis -- Chapter8: Adolescence and Scoliosis: Deciphering the Complex Biology of Puberty and Scoliosis.
520	3		_aOur understanding of the genetic and developmental mechanisms underlying scoliosis is rapidly evolving, this timely second edition of The Genetics and Development of Scoliosis is to provide researchers, clinicians, and students with the most current views in this field. This volume brings together leaders in understanding congenital and idiopathic scoliosis to present the current state of research, and to compare the genetic etiology of these conditions, in order to identify potential shared developmental mechanisms. This book will summarize the recent advances in studies of spinal development and how disruptions during embryogenesis in embryonic segmentation can lead to congenital vertebral defects. In addition, recent reports of genetic loci predisposing patients to develop juvenile and adolescent idiopathic scoliosis will be presented, and key clinical features are reviewed. Finally, there will be discussion of how genetic heterogeneity and gene-environment interactions may contribute to congenital scoliosis and isolated vertebral malformations.
650		7	_aGenética humana _2embne _9140562
650		7	_aFisiología humana _2embne _9140024
700	1		_aKusumi, Kenro _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2010002210 _1http://viaf.org/viaf/106828713 _9101672
700	1		_aDunwoodie, Sally L _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2010002211 _1http://viaf.org/viaf/106828721
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319901480
776	0	8	_iEdición impresa: _z9783319901503
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-90149-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_2018
998			_aSI _b02/2019 _cm _dz _ep _feng _ggw _h0
999			_c100893 _d100893 _x1