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008			180612s2018 gw | s |||| 0|eng d
020			_a9783319781907 _9
024	7		_a10.1007/978-3-319-78190-7 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQD433 2018 EB
245	1	0	_aRNA Metabolism in Mitochondria _cedited by Jorge Cruz-Reyes, Michael W. Gray.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (IX, 249 páginas 39 ilustraciones,37 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aNucleic Acids and Molecular Biology _x0933-1891 _v34
505	0		_aThe mitochondrial transcription machinery -- Mitochondrial RNA turnover in Metazoa -- Mitochondrial RNase P complex in animals: mitochondrial tRNA processing and links to disease -- Intercompartment RNA trafficking in mitochondrial function and communication -- Control mechanisms of the holo-editosome in trypanosomes -- Mitochondrial RNA editing and processing in diplonemid protists -- Mechanisms and evolution of tRNA 5'-editing in mitochondria -- Editing of mitochondrial RNAs in Physarum polycephalum -- Requirement of various protein combinations for each C-to-U RNA editosome in plant organelles
520	3		_aThis volume focuses on mitochondrial RNA metabolism, emphasizing recent discoveries and technological advances in this fast moving area that increase our understanding of mitochondrial gene function. Topics addressed include the interplay of mitochondria with the nucleus and cytosol, structure-function connections, and relevance to human disease. Mitochondria are the powerhouses of the cell, and a great deal is known about mitochondrial energy metabolism. Less well known is the plethora of amazing mechanisms that have evolved to control expression of mitochondrial genomes. Several RNA processes and machineries in protozoa, plants, flies and humans are discussed, including: transcription and RNA polymerase mechanism; tRNA processing of 5' and 3' ends; mRNA maturation by nucleotide insertion/deletion editing and by RNA splicing; mRNA stability; and RNA import. Specialized factors and ribonucleoproteins (RNPs) examined include pentatricopeptide repeat (PPR) proteins, RNase P, polymerases, helicases, nucleases, editing and repair enzymes. Remarkable features of these processes and factors are either not found outside mitochondria, differ substantially among eukaryotic lineages, or are unique in biology. .
650		7	_9140525 _aÁcidos nucleicos _2embne
650		7	_9162770 _aExpresión génica _2embne
650		7	_aMicrobiología _2embne _9138684
700	1		_aCruz-Reyes, Jorge _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/9153288372932652993
700	1		_aGray, Michael W _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2018014286 _1http://viaf.org/viaf/117133834
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319781891
776	0	8	_iEdición impresa: _z9783319781914
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-78190-7 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_2018
998			_aSI _b02/2019 _cm _dz _ep _feng _ggw _h0
999			_c100892 _d100892 _x1