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007			cr nn nnnaamaa
008			180728s2018 gw | s |||| 0|eng d
020			_a9783319908083 _9
024	7		_a10.1007/978-3-319-90808-3 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQP625.A27 2018 EB
245	1	4	_aThe Adenosine Receptors _cedited by Pier Andrea Borea, Katia Varani, Stefania Gessi, Stefania Merighi, Fabrizio Vincenzi.
264		1	_aCham, Switzerland _bSpringer International Publishing : _bImprint: Humana Press _c2018
300			_a1 recurso en línea (XX, 593 páginas 71 ilustraciones,29 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aThe Receptors _x1048-6909 _v34
505	0		_aPurinergic signalling: an historical overview -- Regulation of extracellular adenosine -- Adenosine receptors: structure, distribution and signal transduction -- Binding thermodynamic characteristics of adenosine receptor ligands -- A1 adenosine receptor agonists, antagonists and allosteric modulators -- A2A adenosine receptor: structure, function and medicinal chemistry -- Medicinal chemistry of A2B adenosine receptors -- A3 adenosine receptor: medicinal chemistry of orthosteric and allosteric ligands and structural probing -- Adenosine Receptors and Neuroinflammation -- Adenosine receptors as paradigm to identify dimer/oligomers of G-protein-coupled receptors and as targets in Parkinson's disease -- Adenosine receptors in Alzheimer's disease -- What is the role of adenosine receptors in Huntington Disease? -- Adenosine receptors: a novel target for homeostatic control of cognition -- Role of Adenosine Receptors in Epileptic Seizures -- Adenosine signaling in brain Ischemia -- Adenosine and traumatic brain injury -- Adenosine and its receptors in pain -- Adenosine signalling in the injured heart -- Adenosine receptors in the lungs -- Adenosine and renal function in health and disease -- Adenosine regulation of the immune system -- Adenosine receptors regulate skeletal biology -- Adenosine receptors in gestational diabetes mellitus and obesity -- Adenosine receptors: current research and their involvement in cancer -- Adenosine receptors as a biological pathway for pulsed electromagnetic fields.
520	3		_aThis book traces the history of adenosine receptor research from molecular biology to medicinal chemistry to behavior, including their implications in disease and potential strategies as therapeutic targets. It provides the reader with a comprehensive overview of the adenosine receptors that includes information on all subtypes - A1, A2A, A2B and A3. Aspects addressed include the most up to date information on their functional distribution in the nervous and peripheral systems, behavioral roles in inflammation, cancer, pain and neurological diseases such as Huntington's disease, Epilepsy, Parkinson's disease and Alzheimer's disease.
650		7	_aReceptores de adenosina _2embne _9668551
650		7	_9146728 _aNeuroquímica _2embne
700	1		_aBorea, Pier Andrea. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _0http://id.loc.gov/authorities/names/nb2010001303 _1http://viaf.org/viaf/106822881 _9668658
700	1		_aVarani, Katia. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aGessi, Stefania. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMerighi, Stefania. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aVincenzi, Fabrizio. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/35146824699307630717
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319908076
776	0	8	_iEdición impresa: _z9783319908090
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-90808-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
998			_aSI _a_alco _a_vill _b04/2019 _cm _dz _ek _feng _ggw _h0
999			_c100791 _d100791 _x1