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020 _a9783319749327
_9
024 7 _a10.1007/978-3-319-74932-7
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aRB153 2018 EB
245 1 0 _aMetabolic Interaction in Infection
_cedited by Ricardo Silvestre, Egídio Torrado.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (VIII, 476 páginas 45 ilustraciones,43 ilustraciones a color)
336 _aTexto
_btxt
_2rdacontent
347 _atext file
_bPDF
_2
490 0 _aExperientia Supplementum
_x1664-431X
_v109
505 0 _aPart I: A guide of metabolism during host-pathogen interactions -- 1. Cellular metabolism at a glance -- 2. Interaction between nutrition and metabolism -- 3. Interplay between metabolic sensors and cell signaling -- 4. Alterations on cellular redox states upon infection and implications for host cell homeostasis -- 5. Mitochondrial bioenergetics and dynamics during infection -- 6. Computational systems biology of metabolism in infection -- 7. Metabolomic-based methods in diagnosis and monitoring infection progression -- Part II: Microbial metabolic adaptation and pathogen rewiring of host cell metabolism during infection -- 8. Metabolic host response to intracellular infections -- 9. Protozoan parasites auxotrophies and metabolic dependencies -- 10. Viral manipulation of the host metabolic network -- 11. Metabolic regulation of innate immunity to fungal infection -- 12. Metabolic crosstalk between host and parasitic pathogens -- 13. Microbiome and gut dysbiosis.
520 3 _aThis book focuses on host-pathogen interactions at the metabolic level. It explores the metabolic requirements of the infectious agents, the microbial metabolic pathways that are dedicated to circumvent host immune mechanisms as well as the molecular mechanisms by which pathogens hijack host cell metabolism for their own benefit. Finally, it provides insights on the possible clinical and immunotherapeutic applications, as well as on the available experimental and analytical methods. The contributions break new ground in understanding the metabolic crosstalk between host and pathogen.
650 7 _aInfecciones
_2embne
_9140426
700 1 _aSilvestre, Ricardo.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_1http://viaf.org/viaf/103182389
700 1 _aTorrado, Egídio.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9783319749310
776 0 8 _iEdición impresa:
_z9783319749334
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-74932-7
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aBiomedical and Life Sciences (Springer-11642)
942 _2lcc
998 _aSI
_a_alco
_a_vill
_b03/2019
_cm
_dz
_ea
_feng
_ggw
_h0
999 _c100756
_d100756
_x1