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001			100741
003			ESmaUEC
005			20230102113009.0
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007			cr nn nnnaamaa
008			180910s2018 gw | s |||| 0|eng d
020			_a9783319778129 _9
024	7		_a10.1007/978-3-319-77812-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aRB112.5 2018 EB
245	1	0	_aChannelopathies in Heart Disease _cedited by Dierk Thomas, Carol Ann Remme.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (VI, 437 páginas)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aCardiac and Vascular Biology _x2509-7830
505	0		_aIntroduction -- Part 1: (Dys)function of cardiac ion channels. Cardiac sodium channel (dys)function and inherited arrhythmia syndromes -- Potassium channels in the heart -- Voltage-gated calcium channels and their roles in cardiac electrophysiology -- HCN channels and cardiac pacemaking -- Dysregulation of ionic homeostasis: relevance for cardiac arrhythmias -- Part 2: Cardiac channelopathies: clinical and genetic findings. Long and short QT syndromes -- Brugada syndrome: current perspectives -- Sinus node disease and cardiac conduction disease -- Catecholaminergic polymorphic ventricular tachycardia -- Idiopathic ventricular fibrillation and early repolarization -- Atrial fibrillation -- Genetic testing for inheritable cardiac channelopathies -- Part 3: Research into cardiac channelopathies: new avenues. Novel imaging techniques in cardiac ion channel research -- Transgenic animal models of cardiac channelopathies - benefits and limitations -- Induced pluripotent stem cell-derived cardiomyocytes: towards personalized therapeutic strategies?. .
520	3		_aThis book provides an expert overview on ion channel-related arrhythmia mechanisms, and describes important advances in our understanding of how ion channel dysfunction causes cardiac disease. Both, scientific findings and clinical implications are presented and discussed by scientists who have considerably contributed to the field. The book is organized in three parts: part I treats the molecular and electrophysiological mechanisms of function and dysfunction of ion channels, part II focuses on genetics and clinical findings, whereas part III describes novel research techniques, the use of stem cells and animal models and provides an outlook on future investigations and applications. The book is written for scientists in Cardiovascular Biology and Neuroscience and will be of general interest to Medical Doctors in Cardiology, Cardiac Electrophysiology and related disciplines.
650		7	_aCanales iónicos _9155847 _2embne
650		7	_9138557 _aCardiología _2embne
700	1		_aThomas, Dierk. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/47680979
700	1		_aRemme, Carol Ann. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt _1http://viaf.org/viaf/291787708
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319778112
776	0	8	_iEdición impresa: _z9783319778136
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-77812-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
998			_aSI _a_alco _a_vill _b04/2019 _cm _dz _ek _feng _ggw _h0
999			_c100741 _d100741 _x1