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020 _a9783319941745
_9
024 7 _a10.1007/978-3-319-94174-5
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aTA404.6
245 1 0 _aParticles and Nanoparticles in Pharmaceutical Products :
_bDesign, Manufacturing, Behavior and Performance
_cedited by Henk G. Merkus, Gabriel M. H. Meesters, Wim Oostra.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XII, 446 páginas 110 ilustraciones,46 ilustraciones a color)
336 _aTexto
_btxt
_2rdacontent
347 _atext file
_bPDF
_2
490 0 _aAAPS Advances in the Pharmaceutical Sciences Series,
_x2210-7371
_v29
505 0 _aPreface -- Author Information -- Introduction -- Guide to Pharmaceutical Product Quality -- Bio-Nano: Theranostic at Cellular Level -- Moving Liposome Technology from the Bench to the Oncological Patient: Towards Performance by Design -- Fundamentals of Dry Powder Inhaler Technology -- Blending and Characterization of Pharmaceutical Powders -- Guidance on Drug Substance Particle Size Controls -- Effects of Particle Size, Surface Nature and Crystal Type on Dissolution Rate -- Amorphous APIs: Improved Release, Preparation, Characterization -- Particle Properties: Impact on the Processing and Performance of Oral Extended-Release Hydrophilic Matrix Tablets -- The Role of Particulates in Film Coating of Pharmaceutical Tablets -- Particulates in Semi-solid Pharmaceutical Products -- The Side Effects of Drugs: Nanopathological Hazards and Risks -- Subject Index. .
520 3 _aThis edited volume brings together the expertise of numerous specialists on the topic of particles - their physical, chemical, pharmacological and toxicological characteristics - when they are a component of pharmaceutical products and formulations. The book discusses in detail properties such as the composition, size, shape, surface properties and porosity of particles with respect to how they impact the formulations and products in which they are used and the effective delivery of pharmaceutical active ingredients. It considers all dosage forms of pharmaceuticals involving particles, from powders to tablets, creams to ointments, and solutions to dry-powder inhalers, also including the latest nanomedicine products. Further, it discusses examples of particle toxicity, as well as the important subject of pharmaceutical industry regulations, guidelines and legislation. The book is of interest to researchers and practitioners who work on testing and developing pharmaceutical dosage and delivery systems.
700 1 _aMerkus, Henk G.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_0http://id.loc.gov/authorities/names/nb2009011716
_1http://viaf.org/viaf/88446530
700 1 _aMeesters, Gabriel M. H.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
_1http://viaf.org/viaf/306389392
700 1 _aOostra, Wim.
_eeditor literario
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9783319941738
776 0 8 _iEdición impresa:
_z9783319941752
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-94174-5
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aBiomedical and Life Sciences (Springer-11642)
942 _2lcc
988 _aEBSPRINGER_2018
999 _c100738
_d100738
_x1