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008			180903s2018 gw | s |||| 0|eng d
020			_a9783319167695 _9
024	7		_a10.1007/978-3-319-16769-5 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQM484 2018 EB
245	1	0	_aEpigenetic Regulation of Skin Development and Regeneration _cedited by Vladimir A. Botchkarev, Sarah E. Millar.
264		1	_aCham, Switzerland _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XIII, 323 páginas 27 ilustraciones,24 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aStem Cell Biology and Regenerative Medicine _x2196-8985
505	0		_aPreface -- Chapter 1 All Roads Go to the Nucleus -- Chapter 2 DNA methylation as an epigenetic memory keeper during skin development and regeneration -- Chapter 3 Polycomb genes and their roles in skin development and regeneration -- Chapter 4 Trithorax genes in the control of keratinocyte differentiation -- Chapter 5 Histone deacetylase functions in epidermal development, homeostasis and cancer -- Chapter 6 The role of ATP-dependent chromatin remodeling in the control of epidermal differentiation and skin stem cell activity -- Chapter 7 Orchestrated Role of microRNAs in Skin Development and Regeneration -- Chapter 8 Non-coding genome and its role in the control of gene expression -- Chapter 9 RNA modifications in the control of epidermal differentiation and stem cell activity -- Chapter 10 Enhancer-Promoter Interactions and Their Role in the Control of Epidermal Differentiation -- Chapter 11 Nuclear lamina as an interface between cytoskeleton and chromatin -- Chapter 12 Epigenetic mechanisms in the control of skin wound healing.
520	3		_aThis indispensable volume highlights recent studies identifying epigenetic mechanisms as essential regulators of skin development, stem cell activity and regeneration. Chapters are contributed by leading experts and promote the skin as an accessible model system for studying mechanisms that control organ development and regeneration. The timely discussions contained throughout are of broad relevance to other areas of biology and medicine and can help inform the development of novel therapeutics for skin disorders as well as new approaches to skin regeneration that target the epigenome. Part of the highly successful Stem Cells and Regenerative Medicine series, Epigenetic Regulation of Skin Development and Regeneration uncovers the fundamental significance of epigenetic mechanisms in skin development and regeneration, and emphasizes the development of new therapies for a number of skin disorders, such as pathological conditions of epidermal differentiation, pigmentation and carcinogenesis. At least six categories of researchers will find this book essential, including stem cell, developmental, hair follicle or molecular biologists, and gerontologists or clinical dermatologists.
650		7	_9139588 _aPiel _2embne
650		7	_aCélulas madre _2embne _9160528
700	1		_aBotchkarev, Vladimir A. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aMillar, Sarah E. _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9783319167688
776	0	8	_iEdición impresa: _z9783319167701
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-16769-5 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
998			_aSI _a_alco _a_vill _b04/2019 _cm _dz _ek _feng _ggw _h0
999			_c100732 _d100732 _x1