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020 _a9783319987859
_9
024 7 _a10.1007/978-3-319-98785-9
_2doi
040 _aES-MaUEC
_bspa
_cES-MaUEC
050 4 _aRA761 2018 EB
100 1 _aKampf, Günter
_eautor
_9668874
245 1 0 _aAntiseptic Stewardship :
_bBiocide Resistance and Clinical Implications
_cby Günter Kampf.
264 1 _aCham, Switzerland
_bSpringer International Publishing
_c2018
300 _a1 recurso en línea (XLI, 694 páginas 20 ilustraciones,17 ilustraciones a color)
336 _aTexto
_btxt
_2rdacontent
347 _atext file
_bPDF
_2
505 0 _a1. Chemical characterization -- 2. Types of application -- 2a. Approval by ECHA -- 2b. Approval by EPA -- 2c. Amounts per type of application (overall environmental impact) -- 3. Spectrum of antimicrobial activity -- 3a. Bactericidal activity -- 3b. Fungicidal activity -- 3c. Mycobactericidal activity -- 3d. Virucidal activity -- 3e. Sporicidal activity -- 4. Natural resistances -- 5. Adaptation after exposure -- 5a. Per type of typical application -- 6. 7. Cross-resistance to other biocidal agents -- 8. Cross-resistances to antibiotics -- 9. Proposal for responsible use (antiseptic stewardship).
520 3 _aVVarious antiseptic agents, such as chlorhexidine, are used for different applications, e.g. in healthcare, veterinary medicine, animal production and household products, including cosmetics. However, not all antiseptic agents provide significant health benefits, especially in some products used in human medicine (alcohol-based hand rubs, antimicrobial soaps). While some products (antimicrobial soaps, surface disinfectants, instrument disinfectants, wound antiseptics) may contain one or more biocidal agents with a comparable antimicrobial efficacy but large differences in their potential for microbial adaptation and tolerance. An increased bacterial resistance has been described for various antimicrobial agents, sometimes including a cross-resistance to antibiotics. The book is the first comprehensive reference resource on antiseptic agents, including their efficacy, natural and acquired resistance, adaptation, and cross-resistance. It also discusses their and appropriate use in terms of a balance between their efficacy and the risk of acquired bacterial resistance / tolerance. Focusing on human and veterinary medicine and household products, it helps readers make informed decisions concerning against antiseptic products based on their composition. The book contributes to reduce any unnecessary selection pressure towards emerging pathogens and to keep the powerful antiseptic agents for all those applications that have a clear benefit (e.g. reduction of healthcare-associated infection).
650 7 _aAntisépticos
_9668826
_2embne
650 7 _aEnfermedades infecciosas
_2embne
_9138404
710 2 _aSpringerLink (Online service)
_0http://id.loc.gov/authorities/names/no2005046756
_1http://viaf.org/viaf/148105729
_9106996
776 0 8 _iEdición impresa:
_z9783319987842
776 0 8 _iEdición impresa:
_z9783319987866
856 4 0 _uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-98785-9
_zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490 0 _aBiomedical and Life Sciences (Springer-11642)
942 _2lcc
998 _aSI
_a_alco
_a_vill
_b04/2019
_cm
_dz
_ek
_feng
_ggw
_h0
999 _c100715
_d100715
_x1