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008			180720s2018 si | s |||| 0|eng d
020			_a9789811304842 _9
024	7		_a10.1007/978-981-13-0484-2 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC
050		4	_aQR189.5.A33 _bH58 2018 EB
245	1	0	_aHIV Vaccines and Cure : _bThe Path Towards Finding an Effective Cure and Vaccine _cedited by Linqi Zhang, Sharon R. Lewin.
264		1	_aSingapore _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XV, 318 páginas 21 ilustraciones,16 ilustraciones a color)
336			_aTexto _btxt _2rdacontent
347			_atext file _bPDF _2
490	0		_aAdvances in Experimental Medicine and Biology _x0065-2598 _v1075
505	0		_aHIV Vaccine Efficacy Trials: RV144 and beyond -- HIV T-cell vaccines -- HIV broadly neutralizing antibodies: VRC01 and beyond -- Structural features of broadly neutralizing antibodies and rational design of vaccine -- Monkey models and HIV vaccine research -- Treatment of HIV for the Prevention of Transmission in Discordant Couples and at the Population Level -- HIV persistence on antiretroviral therapy and barriers to a cure -- The molecular biology of HIV latency -- Cellular determinants of HIV persistence on antiretroviral therapy -- In Vitro and In Vivo Models of HIV Latency -- Measuring HIV persistence on antiretroviral therapy -- Clinical interventions in HIV cure research.
520	3		_aThis book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition, strategies being tested to eliminate persistent HIV and the rational design of vaccines to induce protective immunity are covered. This book also discusses the challenges related to the design of clinical trials for testing the safety and efficacy of these innovative approaches. This book will provide a systematic overview and also discuss controversial issues for researchers in virology and immunology, as well as practicing physicians, and scientists in the pharmaceutical industry.
650		7	_aVacunas antisida _9667659 _2embne
650		7	_aInmunología _2embne _9138330
700	1		_aZhang, Linqi _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
700	1		_aLewin, Sharon R _eeditor literario _4edt _4http://id.loc.gov/vocabulary/relators/edt
710	2		_aSpringerLink (Online service) _0http://id.loc.gov/authorities/names/no2005046756 _1http://viaf.org/viaf/148105729 _9106996
776	0	8	_iEdición impresa: _z9789811304835
776	0	8	_iEdición impresa: _z9789811304859
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-981-13-0484-2 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aBiomedical and Life Sciences (Springer-11642)
942			_2lcc
988			_aEBSPRINGER_2018
998			_aSI _a_alco _a_vill _b02/2019 _cm _dz _ek _feng _ggw _h0
999			_c100672 _d100672 _x1