000			03307nam a22003855i 4500
001			100452
003			DE-He213
005			20230102112956.0
007			cr nn 008mamaa
008			180222s2018 gw | s |||| 0|eng d
020			_a9783319405223 _9
024	7		_a10.1007/978-3-319-40522-3 _2doi
040			_aES-MaUEC _bspa
050		4	_aQP88.15 2018 EB
100	1		_aCinti, Saverio _eautor _4aut _4http://id.loc.gov/vocabulary/relators/aut _0http://id.loc.gov/authorities/names/n2001129702 _0http://viaf.org/viaf/41193945
245	1	0	_aObesity, Type 2 Diabetes and the Adipose Organ: _bA Pictorial Atlas from Research to Clinical Applications _cby Saverio Cinti.
250			_a2nd edition
264		1	_aCham _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XIII, 455 páginas 190 ilustraciones, 60 ilustraciones a color)
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
505	0		_aThe Adipose Organ -- Brown Adipose Tissue (BAT) -- White Adipose Tissue (WAT) -- The Adipose Organ: Cold Acclimation -- BAT -- WAT -- The Adipose Organ: Warm Acclimation: BAT -- The Obese Adipose Organ: BAT -- The Fasted Adipose Organ: WAT -- BAT -- The Adipose Organ During Lactation: WAT -- BAT -- The Fetal Adipose Organ -- The Adipose Organ In Genetically Modified Models.  .
520	3		_aThis richly illustrated book provides a detailed description of the gross anatomy, light microscopy, immunohistochemistry, and electron microscopy of the adipose organ, which comprises subcutaneous and visceral fat depots. Findings in mice of differing genetic backgrounds (obesity prone and resistant) and maintained in standard and various physiologic and pathologic conditions are presented. The latter conditions include chronic cold exposure, warm exposure, fasting, pregnancy-lactation, and obesity. Features of the fetal adipose organ are described in a separate chapter, and results from transgenic mice are also presented when relevant. The human adipose organ is addressed in several chapters that include magnetic resonance and fetal findings. Most of the results regarding the adipose organ anatomy in different physiologic conditions are new, and the story of pink adipocytes (white-to-pink transdifferentiation) is quite innovative. The concept of using browning of the adipose organ as a therapeutic tool for obesity must take into consideration the anatomic and morphologic aspects described here, and the study of pink adipocytes could lead to a better comprehension of breast cancer tumor biology. This book will be of interest to all scientists who deal with obesity and related disorders.
650		7	_9667182 _aTejido adiposo _2embne
650		7	_aDiabetes _9138582 _2embne
650		7	_aEndocrinología _2embne _9139372
776	0	8	_iEdición impresa: _z9783319405209
776	0	8	_iEdición impresa: _z9783319405216
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-319-40522-3 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
490	0		_aMedicine (Springer-11650)
988			_aSpringer_Medicine_2018
998			_b01/2019 _dz _ef _feng _ggw _h0
999			_c100452 _d100452 _x1