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008			180209s2018 gw | fo |||| 0|eng d
020			_a9783662561799
024	7		_a10.1007/978-3-662-56179-9 _2doi
040			_aES-MaUEC _bspa _cES-MaUEC _dES-MaUEC
041	0		_aeng
050		4	_aQH499 _b2018 EB
100	1		_aFu, Xiaobing _eautor _9672993
245	1	0	_aCellular Dedifferentiation and Regenerative Medicine _cby Xiaobing Fu, Andong Zhao, Tian Hu
264		1	_aBerlin, Heidelberg _bSpringer International Publishing _c2018
300			_a1 recurso en línea (XII, 291 páginas) _b27 ilustraciones, 21 ilustraciones a color
336			_2rdacontent _aTexto _btxt
337			_2rdamedia _aelectrónico _bc
338			_2rdacarrier _arecurso electrónico _bcr
347			_atext file _bPDF
490	0		_aMedicine (Springer-11650)
505	0		_aA brief history of Regeneration -- The origin of cells in Regeneration -- Cell dedifferentiation -- Cell transdifferentiation -- Cell reprogramming -- Dedifferentiation vs Transdifferentiation vs Reprogramming -- The extent of cell dedifferentiation -- Maintenance of cell differentiated identity -- Unstable differentiated state -- Epidermal cell dedifferentiation and skin regeneration -- Peripheral nerve regeneration and Schwann cell dedifferentiation -- Central nervous system and dedifferentiation -- Dedifferentiation and Heart -- Dedifferentiation and Kidney -- Dedifferentiation and other 4 systems -- The relationship between cell dedifferentiation and development of cancer and several diseases.
520	3		_aThis book focuses on the contribution of cell dedifferentiation to the regenerative process in all body systems, as well as its underlying molecular mechanisms and applications. The book is divided into four parts, the first of which addresses the history of cell dedifferentiation and regenerative medicine. In turn, Part II compares three routes by which cells change their phenotype: dedifferentiation, transdifferentiation, and reprogramming. Part III includes an extensive review of cell dedifferentiation events in all nine body systems for lower organisms and mammalians, respectively. The final part reviews the relationship between cell dedifferentiation and the development of cancer and several other diseases, while also outlining the prospects of and future research directions in cell dedifferentiation and regenerative medicine. The main purpose of the book is to underline the importance of cell dedifferentiation in stem cell and regenerative medicine by providing a systematical review of dedifferentiation in all body systems, together with the latest reliable evidence.
988			_aSpringer_Medicine_2018
650		7	_2embne _9148273 _aRegeneración (Biología)
700	1		_aZhao, Andong. _eautor. _0http://id.loc.gov/authorities/names/nr91035667 _0http://viaf.org/viaf/31854936
700	1		_aHu, Tian. _eautor. _0http://id.loc.gov/authorities/names/n2018186661 _0http://viaf.org/viaf/10152138512310981061
776	0	8	_iEdición impresa: _z9783662561775
776	0	8	_iEdición impresa: _z9783662561782
776	0	8	_iEdición impresa: _z9783662572573
856	4	0	_uhttps://go.openathens.net/redirector/universidadeuropea.es?url=https://doi.org/10.1007/978-3-662-56179-9 _zAcceso a este recurso digital (usuarios Universidad Europea de Madrid)
942			_2lcc _cLE _n0
998			_b04/2020 _dz _eb _zSI