Preface; Organization and Content; Series Editors; Volume Editors; Contents; Contributors; Part I: Basic Phosphorus Physiology; 1: The Story of Phosphorus; Introduction; Terminology: So Many Names but One Meaning; The Story of Phosphorus: From Serendipity to Novelty Item; From Novelty to Utility: Early Uses of Phosphorus; References; 2: Overview of Phosphorus Homeostasis; Introduction; Phosphorus Balance: Gastrointestinal Absorption; Intestinal Epithelial Luminal Membrane Transport; Transcellular Movement of Phosphorus; Phosphate Exit at Basolateral Membrane

3: Hormonal Regulation of Phosphorus Homeostasis: Parathyroid Hormone, Fibroblast Growth Factor 23, and Klotho Introduction; In Vivo Phosphate Turnover; Fibroblast Growth Factor 23; FGF23 and Chronic Kidney Disease; Klotho and Its Structure; FGF23-Klotho Signaling Pathways; Klotho and Systemic FGF23 Function; Concluding Remarks; References; Part II: Phosphorus in Food; 4: Phosphorus in the Modern Food Supply: Underestimation of Exposure; Introduction; Phosphorus Content of Food; Evidence of Excess Dietary Phosphorus Intake Relative to Requirements

Importance of the Type and Physiologic Effects of Phosphorus in Food Natural or Organic Phosphorus; Added or Inorganic Phosphorus; Safety of Current Phosphorus Intakes Relative to Calcium Intakes; Summary and Conclusions; References; 5: Nutritional Aspects of Phosphorus Compounds in Foods; Introduction; Distribution of Body Phosphorus; Criteria for Dietary Reference Intakes (DRI): Phosphorus [11]; Phosphorus Balance; Serum Phosphorus; Factorial Method; Infants: Birth to 12 Months; Infants: Preterm; Dietary Phosphorus in Bone Health; Refeeding Syndrome

Phosphorus and Specialized Nutrition Support Hypophosphatemia and Phosphate Depletion; Hungry Bone Syndrome; Dietary Phosphorus Needs in Patients with Chronic Kidney Disease (CKD); References; 6: Phosphorus Additives in Food Processing; Introduction; Bakery and Cereal Products; Phosphates in Meat, Poultry, and Seafood Processing; Dairy Foods; Dairy Desserts; Beverage Applications; Potato Processing; Other Uses of Food-Grade Phosphates; References; 7: Effects of Natural and Added Phosphorus Compounds in Foods in Health and Disease; Introduction; Phosphorus in Food

Renal Excretion of Phosphorus, Reabsorption Comparison of Superficial and Deep Nephron Transport; Cellular Mechanisms of Phosphate Reabsorption in the Kidney; Proteins That Interact with the Type IIa Na/Pi Cotransporter Protein; Regulation of Homeostasis by Factors That Affect the Urinary Excretion of Phosphorus; Alterations in Dietary Phosphorus Intake; Effects of PTH on Phosphorus Reabsorption by the Kidney; Fibroblast Growth Factor 23 (FGF23); Other Regulatory Factors; Phosphate Homeostasis in Chronic Kidney Disease; References