Introduction to sedation and analgesia -- Monitoring sedation and analgesia -- Analgesic Agents -- Regional analgesia and its role in the PICU -- Benzos -- Alpha agonists in pediatric critical care -- barbiturates -- ketamine -- propofol -- inhalational agents -- tolerance and withdrawal -- neuromuscular blockade -- cardiac surgical patients -- neonates -- TBI/brain injury -- neurotoxicity -- sedation/analgesia for endotracheal intubation -- sleep in the PICU -- delirium -- Mobility in the PICU -- Palliative Sedation -- Child Life in the PICU -- Introduction to procedural sedation within and outside of the ICU -- Pre-sedation assessment -- choosing a sedation -- Analgesics -- Sedatives (benzodiazepines and barbiturates) -- Sedatives ( Dexmedetomidine) -- i. Ketamine -- ii. Propofol -- Nitrous oxide -- Non-pharmacologic adjuncts/Child Life -- High risk sedations (cardiac, obesity, ex-premature, autism, OSA, upper resp infections) -- Nursing considerations -- sedation simulation

This book provides a comprehensive overview on sedation and analgesia for the pediatric intensivist. Divided into two primary sections, the text presents a framework on how to care for patients who need sedation, analgesia, and neuromuscular blockade inside the pediatric ICU (PICU), and how to manage procedural sedation in an outpatient setting. The first section focuses on sedation and analgesia for the critically ill child, with an emphasis on analgesics, sedatives, neuromuscular blockade, tolerance and withdrawal, and the PICU environment. The second section centers around procedural sedation, detailing patient selection, pre-sedation assessment, how to choose a sedation regimen, available agents, and nursing considerations. Written by experts in the field, Sedation and Analgesia for the Pediatric Intensivist: A Clinical Guide is a valuable resource for the pediatric intensivist in caring for their patients both inside and outside the PICU.