SpringerLink Springer Biomedical and Life Sciences eBooks 2017 English+International

Incluye referencias bibliográficas

Mammalian actins: isoform-specific functions and diseases / Christophe Ampe, Marleen Van Troys -- Assembly and maintenance of myofibrils in striated muscle / Joseph W. Sanger, Jushuo Wang, Yingli Fan, Jennifer White, Lei Mi-Mi, Dipak K. Dube [and others] -- Myosins: domain organisation, motor properties, physiological roles and cellular functions / Thomas A. Masters, John Kendrick-Jones, Folma Buss -- Actin filament structures in migrating cells / Jaakko Lehtimäki, Markku Hakala, Pekka Lappalainen -- Signalling pathways controlling cellular actin organization / Anika Steffen, Theresia E.B. Stradal, Klemens Rottner -- Adp-ribosylation and cross-linking of actin by bacterial protein toxins / Klaus Aktories, Carsten Schwan, Alexander E. Lang -- Common themes in cytoskeletal remodeling by intracellular bacterial effectors / Guy Tran Van Nhieu, Stéphane Romero -- Viruses that exploit actin-based motility for their replication and spread / N. Bishara Marzook, Timothy P. Newsome -- Multiscale view of cytoskeletal mechanoregulation of cell and tissue polarity / Chen Luxenburg, Benjamin Geiger -- Molecular control of actin dynamics in vivo: insights from drosophila / Lena Brüser, Sven Bogdan -- From cytoskeleton to gene expression: actin in the nucleus / Tiina Viita, Maria K. Vartiainen -- What we know and do not know about actin / Thomas D. Pollard.

"Actin is one of the most abundant proteins and ubiquitously expressed in all eukaryotes. In recent years, the analysis of structure and function of such complexes has shed new light on actin's role in cellular and tissue morphogenesis, locomotion and various forms of intracellular motility, but also on its role in nuclear processes like chromatin architecture and transcription. Progress in understanding these different physiological phenomena, but also in unravelling the basis of actin-based pathophysiological processes has been made by combining video microscopy, molecular biology, genetics and biochemistry. Thus, the current research on actin, as ongoing in many international laboratories, is a "hot spot" in basic and translational research in life sciences. In this book on "The Actin Cytoskeleton", twelve internationally renowned authors present specific chapters that cover their recent work concerned with the various roles of actin mentioned above. This comprehensive volume is therefore an attractive handbook for teachers and students in many fields of medicine and pharmacology"--Publisher's description.