Pathophysiology: The target for renal denervation -- Physiological Rationale forÂ{u296E}al Denervation Therapy in Hypertension -- Preclinical Model and Histopathology Translational Medicine and Renal Denervation.-Â{u4A25} endpoint on measuring the clinical effects of renal denervation:Âרat are the best surrogates -- Appraisal of the Clinical Trial Data on Renal Denervation for the Management of Resistant Hypertension -- Catheter-Based Technology Alternatives for Renal Denervation: An Overview -- Medtronic ardian symplicityâ{u2832}enal denervation devices -- Sympathetic Renal Denervation Using the EnligHTN Multi-electrode Ablation System: The St Jude Experience -- ReCor Medical Paradise® Renal Denervation System -- Therapeutic Intra Vascular Ultrasound (TIVUS) -- The “OneShotâ€{u0272}rigated Balloon-Mounted Spiral Electrode Renal Denervation Device -- NOVOSTE: The Brachytherapy Approach to Renal Denervation -- Perivascular Renal Denervation (PVRDTM): Chemical Renal Denervation With Micro-doses of Ethanol Using the PeregrineTM Renal Denervation Device -- Vincristine Local Delivery for Renal Artery Denervation.-Â{uE970}phroBlateâ{u2812}enal Denervation System: Urologic-nephrologic Based Approach to Resistant Hypertension -- Targeted renal nerve deactivation by neurotropic agents -- Boston Scientific Vessixâ{u2812}enal Denervation System -- Radiofrequency and irrigated ablation â€{u0C32}inciples and potential for renal artery denervation (RDN) in the treatment of resistant arterial hypertension -- Renal denervation: Potential futureÂ{u0A6D}plications beyond resistant hypertension -- Renal Denervation for Congestive Heart Failure -- Great myths of blood pressure effect size in renal denervation.-Â{u4A25} Potential Role of Catheter-based Renal Sympathetic Denervation in Chronic and End Stage Kidney Disease -- Diabetes and Metabolic Syndrome.-Â{u03E2}structive sleep apnea.

This book examines renal pathophysiology and the rationale for renal denervation (RDN), a minimally invasive, endovascular catheter based procedure using radiofrequency ablation for the treatment of resistant hypertension, a leading cause of morbidity and mortality in western civilization. In addition, the possible long term benefits and risks of this new therapy are discussed together with a description of the myriad of currently available devices and approaches involved in the evolution of this treatment. Lastly, the book focuses on the cost effectiveness of renal denervation and future directions for other possible benefits.Âײitten by world renowned leaders in the field, Renal Denervation will be of immediate use to cardiologists, nephrologists and urologists as well as allied health professionals, device companies and anyone working in this field. Â{uE032}