SpringerLink Springer Biomedical and Life Sciences eBooks 2017 English+International

880-01 Foreword; Contents; Contents for Volume 2; Part I: Physiology; A Brief History of Blood Platelets: A Personal View; Introduction; The Discovery of Blood Platelets and Early Research; The 1960s; The 1970s; The 1980s and 1990s; References; Phylogeny of Blood Platelets; Introduction; Phylogeny of Platelets; Phylogeny of Platelet Molecules and Receptors; References; Platelet Morphology and Ultrastructure; Overall Morphology and Function of Platelets; Visualization of Platelets; The Resting Platelet Ultrastructure; The Open Canalicular System; The Dense Tubular System; Peroxisomes; Mitochondria.

Age- and Maturation-Related Platelet HeterogeneityHeterogeneity of Platelet Genetics; Heterogeneity of Activated Platelets (Procoagulant Platelets); Platelet Heterogeneity Within the Hemostatic Plug and Thrombus; References; Regulation of Platelet Adhesion Receptors; Introduction; Regulation of Platelet Integrins; Positive Regulators of Integrin Activation; ``Classical F́́luid-Phase Excitatory Platelet Agonists; ``Nonclassical É́xcitatory Agonists; Matrix-Associated Platelet Agonists Functioning Through Hemostatic Pathways; Platelet Agonists Functioning Through Non-hemostatic Pathways.

This book reviews current science and applications in fields including thrombosis and hemostasis, signal transduction, and non-thrombotic conditions such as inflammation, allergy and tumor metastasis. It is a detailed, up-to-date, highly referenced text for clinical scientists and physicians, including recent developments in this rapidly expanding field. More than a scientific resource, this is also an authoritative reference and guide to the diagnosis.