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Cardiac regeneration / Masaki Ieda, Wolfram-Hubertus Zimmermann, editors.

Contributor(s): Ieda, Masaki,, editor literario | Zimmermann, Wolfram-Hubertus,, editor literario
Material type: materialTypeLabelE-bookSeries: (Cardiac and vascular biology).Publisher: Cham, Switzerland : Springer International Publishing, 2017Description: 1 recurso en línea.ISBN: 3319561065; 9783319561066.Subject: CardiologíaOnline resources: Acceso a este recurso digital (usuarios Universidad Europea de Madrid)Digital Resources
Contents:
""Preface""; ""Contents""; ""1: Past and Future of Cell-Based Heart Repair""; ""1.1 Introduction""; ""1.2 Cell Therapy for Cardiac Repair""; ""1.2.1 Skeletal Myoblasts""; ""1.2.2 Bone Marrow-Derived Stem Cells""; ""1.2.3 Endothelial Progenitors""; ""1.2.4 Mesenchymal Stem Cells""; ""1.2.5 Endogenous Cardiac Stem Cells""; ""1.2.5.1 C-kit + Cardiac Progenitors""; ""1.2.5.2 Cardiosphere and Cardiosphere-Derived Cells""; ""1.2.5.3 Side Population Cells""; ""1.2.5.4 Sca1+ Cardiac Progenitors""; ""1.2.5.5 Islet1+ Cardiac Progenitors""; ""1.2.5.6 Epicardial Progenitors""
""1.2.6 ES-Derived Cardiomyocytes""""1.2.7 Induced Pluripotent Stem Cells and Reprogramming""; ""1.2.7.1 iPSCs""; ""1.2.7.2 Direct Reprogramming into Cardiomyocytes""; ""1.3 Future of Cell Therapy""; ""References""; ""2: Progenitor Cells from the Adult Heart""; ""2.1 Phenotype and Characteristics of eCSCs""; ""2.1.1 c-kitpos Stem and Progenitor Cells""; ""2.1.2 Sca-1pos and Side Population Progenitor Cells""; ""2.2 Cardiac Differentiation Potential of eCSCs""; ""2.3 The Controversy""; ""2.4 Origin of eCSCs""; ""2.5 Impact of Ageing and Senescence on eCSCs""
""2.6 Therapeutic Targets to Activate eCSCs and Reverse the Senescent, Dysfunctional eCSC Phenotype""""References""; ""3: Epicardial Progenitors in the Embryonic and Adult Heart""; ""3.1 Epicardial Development Across Species""; ""3.2 EPDC Derivatives and Epicardial Heterogeneity""; ""3.2.1 Epicardium Contribution to Coronary Endothelial Cells""; ""3.2.2 Epicardial Contribution to Cardiomyocytes""; ""3.2.3 Epicardial Contribution to Fat Cells""; ""3.3 The Epicardium as a Signaling Center in the Developing Heart""
""3.3.1 Epicardial Signals Promoting Cardiomyocyte Proliferation""""3.3.2 Epicardial Signals Directing Coronary Angiogenesis""; ""3.3.3 Other Epicardial Signals Contributing to Heart Development""; ""3.4 Adult Epicardium""; ""3.4.1 Physiological Role of the Epicardium in Homeostatic Conditions""; ""3.4.2 The Epicardium to Regenerate the Adult Heart""; ""3.5 Human Epicardium""; ""References""; ""4: Generation and Application of Human Pluripotent Stem Cell-Derived Cardiomyocytes""; ""4.1 Introduction""; ""4.2 Applications""; ""4.2.1 Regenerative Medicine""
""4.2.2 Biological Pacemaker Development""""4.2.3 Understanding of Human Cardiac Development""; ""4.2.4 Disease Modeling""; ""4.2.5 Drug Discovery, Pharmacogenomics, and Cardiotoxicity Screening""; ""4.3 Cardiomyogenesis during Mammalian Heart Development""; ""4.4 Control of the Pluripotent State""; ""4.5 Human Pluripotent Growth Media""; ""4.6 Priming for Cardiac Differentiation""; ""4.7 Maintenance of hiPSC-Derived Mesodermal Intermediates and Cardiac Progenitor Cells""; ""4.8 Directed Cardiac Differentiation of Human Pluripotent Stem Cells""
Abstract: This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.
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Holdings
Item type Current library Collection Call number Status Date due Barcode Item holds
LIBRO-E NO PRÉSTAMO LIBRO-E NO PRÉSTAMO Madrid Digital Acceso Electrónico (UEM) Ciencias de la Salud RC683.8 .I43 2017 EB (Browse shelf(Opens below)) Acceso electrónico eBook.20024258
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Incluye referencias bibliográficas

""Preface""; ""Contents""; ""1: Past and Future of Cell-Based Heart Repair""; ""1.1 Introduction""; ""1.2 Cell Therapy for Cardiac Repair""; ""1.2.1 Skeletal Myoblasts""; ""1.2.2 Bone Marrow-Derived Stem Cells""; ""1.2.3 Endothelial Progenitors""; ""1.2.4 Mesenchymal Stem Cells""; ""1.2.5 Endogenous Cardiac Stem Cells""; ""1.2.5.1 C-kit + Cardiac Progenitors""; ""1.2.5.2 Cardiosphere and Cardiosphere-Derived Cells""; ""1.2.5.3 Side Population Cells""; ""1.2.5.4 Sca1+ Cardiac Progenitors""; ""1.2.5.5 Islet1+ Cardiac Progenitors""; ""1.2.5.6 Epicardial Progenitors""

""1.2.6 ES-Derived Cardiomyocytes""""1.2.7 Induced Pluripotent Stem Cells and Reprogramming""; ""1.2.7.1 iPSCs""; ""1.2.7.2 Direct Reprogramming into Cardiomyocytes""; ""1.3 Future of Cell Therapy""; ""References""; ""2: Progenitor Cells from the Adult Heart""; ""2.1 Phenotype and Characteristics of eCSCs""; ""2.1.1 c-kitpos Stem and Progenitor Cells""; ""2.1.2 Sca-1pos and Side Population Progenitor Cells""; ""2.2 Cardiac Differentiation Potential of eCSCs""; ""2.3 The Controversy""; ""2.4 Origin of eCSCs""; ""2.5 Impact of Ageing and Senescence on eCSCs""

""2.6 Therapeutic Targets to Activate eCSCs and Reverse the Senescent, Dysfunctional eCSC Phenotype""""References""; ""3: Epicardial Progenitors in the Embryonic and Adult Heart""; ""3.1 Epicardial Development Across Species""; ""3.2 EPDC Derivatives and Epicardial Heterogeneity""; ""3.2.1 Epicardium Contribution to Coronary Endothelial Cells""; ""3.2.2 Epicardial Contribution to Cardiomyocytes""; ""3.2.3 Epicardial Contribution to Fat Cells""; ""3.3 The Epicardium as a Signaling Center in the Developing Heart""

""3.3.1 Epicardial Signals Promoting Cardiomyocyte Proliferation""""3.3.2 Epicardial Signals Directing Coronary Angiogenesis""; ""3.3.3 Other Epicardial Signals Contributing to Heart Development""; ""3.4 Adult Epicardium""; ""3.4.1 Physiological Role of the Epicardium in Homeostatic Conditions""; ""3.4.2 The Epicardium to Regenerate the Adult Heart""; ""3.5 Human Epicardium""; ""References""; ""4: Generation and Application of Human Pluripotent Stem Cell-Derived Cardiomyocytes""; ""4.1 Introduction""; ""4.2 Applications""; ""4.2.1 Regenerative Medicine""

""4.2.2 Biological Pacemaker Development""""4.2.3 Understanding of Human Cardiac Development""; ""4.2.4 Disease Modeling""; ""4.2.5 Drug Discovery, Pharmacogenomics, and Cardiotoxicity Screening""; ""4.3 Cardiomyogenesis during Mammalian Heart Development""; ""4.4 Control of the Pluripotent State""; ""4.5 Human Pluripotent Growth Media""; ""4.6 Priming for Cardiac Differentiation""; ""4.7 Maintenance of hiPSC-Derived Mesodermal Intermediates and Cardiac Progenitor Cells""; ""4.8 Directed Cardiac Differentiation of Human Pluripotent Stem Cells""

This Volume of the series Cardiac and Vascular Biology offers a comprehensive and exciting, state-of-the-art work on the current options and potentials of cardiac regeneration and repair. Several techniques and approaches have been developed for heart failure repair: direct injection of cells, programming of scar tissue into functional myocardium, and tissue-engineered heart muscle support. The book introduces the rationale for these different approaches in cell-based heart regeneration and discusses the most important considerations for clinical translation. Expert authors discuss when, why, and how heart muscle can be salvaged. The book represents a valuable resource for stem cell researchers, cardiologists, bioengineers, and biomedical scientists studying cardiac function and regeneration.

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